Etiologic Agents of Bacterial Sepsis and Their Antibiotic Susceptibility Patterns among Patients Living with Human Immunodeficiency Virus at Gondar University Teaching Hospital, Northwest Ethiopia.

Background. Bacterial sepsis is a major cause of illness in human immunodeficiency virus infected patients. There is scarce evidence about sepsis among HIV patients in Ethiopia. This study aimed to determine the etiologic agents of bacterial sepsis and their antibiotic susceptibility patterns among...

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Publicado en:BioMed Research International Vol. 2016; pp. 1 - 9
Autores principales: Alebachew, Gelila, Teka, Brhanu, Endris, Mengistu, Shiferaw, Yitayal, Tessema, Belay
Formato: research tables/charts Journal Article
Publicado: Wiley-Blackwell 5/23/2016
Acceso en línea:Ver este registro en EBSCOhost
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      dt: 5/23/2016
      vid: 2016
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      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        10.1155/2016/5371875
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        atl: Etiologic Agents of Bacterial Sepsis and Their Antibiotic Susceptibility Patterns among Patients Living with Human Immunodeficiency Virus at Gondar University Teaching Hospital, Northwest Ethiopia.
      aug:
        au:
          Alebachew, Gelila
          Teka, Brhanu
          Endris, Mengistu
          Shiferaw, Yitayal
          Tessema, Belay
        affil: Department of Medical Microbiology, School of Biomedical and Laboratory Sciences, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia
      sug:
        subj:
          Sepsis Etiology
          Sepsis Diagnosis
          Antibiotics Administration and Dosage
          Human
          Academic Medical Centers
          Ethiopia
          Geographic Locations
          Human Immunodeficiency Virus
          HIV Infections Diagnosis
          HIV-Positive Persons
          Blood Chemical Analysis
          Staphylococcal Infections Diagnosis
          Streptococcal Infections Diagnosis
          Bacterial Infections
          Drug Resistance, Microbial
          Antiretroviral Therapy, Highly Active
          Data Collection
          Questionnaires
          Laboratory Chemicals
          Cell Culture Techniques
          Socioeconomic Factors
          Urban Areas
          Rural Areas
          Education
          Marriage
          Work
          Data Analysis
          Data Analysis Software
      ab: Background. Bacterial sepsis is a major cause of illness in human immunodeficiency virus infected patients. There is scarce evidence about sepsis among HIV patients in Ethiopia. This study aimed to determine the etiologic agents of bacterial sepsis and their antibiotic susceptibility patterns among HIV infected patients. Methods. A cross-sectional study was carried out from March 1 to May 2, 2013. One hundred patients infected with HIV and suspected of having sepsis were included. Sociodemographic data were collected by interview and blood sample was aseptically collected from study participants. All blood cultures were incubated aerobically at 35°C and inspected daily for 7 days. The positive blood cultures were identified following the standard procedures and antimicrobial susceptibility testing was performed using disk diffusion technique. Data was entered by Epi-info version 3.5.1 and analysis was done using SPSS version 20. Results. Of the study participants, 31 (31%) confirmed bacterial sepsis. The major isolates were 13 (13%) Staphylococcus aureus, 8 (8%) coagulates negative staphylococci, and 3 (3%) viridans streptococci. Majority of the isolates, 25 (80.6%), were multidrug resistant to two or more antimicrobial agents. Conclusions. Bacterial sepsis was a major cause of admission for HIV infected patients predominated by Staphylococcus aureus and coagulase negative staphylococci species and most of the isolates were multidrug resistant.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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