Mucocutaneous Relapse as an Unusual Presentation of T-Lineage Acute Lymphoblastic Leukemia.
Acute leukemias represent approximately 30% of malignant diseases in patients under the age of 15 years. Leukemic infiltration of the central nervous system and testis are common events, particularly as sites of relapse in the third year after diagnosis. Management of acute lymphoblastic leukemia is...
| Publicado en: | Middle East Journal of Cancer Vol. 7; no. 1; pp. 63 - 67 |
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| Autores principales: | , , |
| Formato: | case study pictorial Journal Article |
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Middle East Journal of Cancer
Jan2016
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=115850925&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 115850925 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 20086709 B7LE jtl: Middle East Journal of Cancer issn: 20086709 maglogo: N pubinfo: dt: Jan2016 vid: 7 iid: 1 pid: 67247 pub: Middle East Journal of Cancer artinfo: ui: 115850925 115850925 115850925 115850925 ppf: 63 ppct: 4 formats: fmt: @attributes: type: P tig: atl: Mucocutaneous Relapse as an Unusual Presentation of T-Lineage Acute Lymphoblastic Leukemia. aug: au: Shahriari, Mahdi Fathpour, Gholamreza Saleh, Fazl affil: Department of Pediatrics, Hematology Oncology Branch, Shiraz University of Medical Sciences, Shiraz, Iran sug: subj: Leukemia, Lymphocytic, Acute T Lymphocytes Recurrence Bone Marrow Palate Adolescence Child Adult Adolescent: 13-18 years Child: 6-12 years Adult: 19-44 years ab: Acute leukemias represent approximately 30% of malignant diseases in patients under the age of 15 years. Leukemic infiltration of the central nervous system and testis are common events, particularly as sites of relapse in the third year after diagnosis. Management of acute lymphoblastic leukemia is based on long-term chemotherapy, leading to a cure rate of approximately 80% of children and adolescents. Despite this elevated cure rate, approximately 20% have disease relapse. Bone marrow is the most frequent site of relapse followed by the central nervous system. Nevertheless, relapse can occur in any tissue or organ. Recurrence in the mucocutaneous area is extremely uncommon and rare in childhood acute lymphoblastic leukemia. To our knowledge, a few case reports (mostly in adolescents or adults) have been published regarding relapse in the mucosal area (oral cavity) and skin. Most patients had concomitant bone marrow relapse. In this paper we report a case of recurrence of T-cell acute lymphoblastic leukemia in the hard palate, lip and skin of a child without bone marrow relapse. pubtype: Academic Journal doctype: case study pictorial Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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