Applying Under-Sampling Techniques and Cost-Sensitive Learning Methods on Risk Assessment of Breast Cancer.

Breast cancer is one of the most common cause of cancer mortality. Early detection through mammography screening could significantly reduce mortality from breast cancer. However, most of screening methods may consume large amount of resources. We propose a computational model, which is solely based...

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Publicado en:Journal of Medical Systems Vol. 39; no. 4; pp. 1 - 14
Autores principales: Hsu, Jia-Lien, Hung, Ping-Cheng, Lin, Hung-Yen, Hsieh, Chung-Ho
Formato: equations & formulas research tables/charts Journal Article
Publicado: Springer Nature Apr2015
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Apr2015
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      pub: Springer Nature
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        atl: Applying Under-Sampling Techniques and Cost-Sensitive Learning Methods on Risk Assessment of Breast Cancer.
      aug:
        au:
          Hsu, Jia-Lien
          Hung, Ping-Cheng
          Lin, Hung-Yen
          Hsieh, Chung-Ho
        affil: Department of Computer Science and Information Engineering, Fu Jen Catholic University, New Tapei City Republic of China
      sug:
        subj:
          Breast Neoplasms Diagnosis
          Risk Assessment
          Cancer Screening
          Models, Statistical
          Breast Neoplasms Risk Factors
          Health Information
          Human
          Taiwan
          Sensitivity and Specificity
          Descriptive Statistics
          Sampling Methods
          Experimental Studies
          Sample Size
          Costs and Cost Analysis
          ROC Curve
      ab: Breast cancer is one of the most common cause of cancer mortality. Early detection through mammography screening could significantly reduce mortality from breast cancer. However, most of screening methods may consume large amount of resources. We propose a computational model, which is solely based on personal health information, for breast cancer risk assessment. Our model can be served as a pre-screening program in the low-cost setting. In our study, the data set, consisting of 3976 records, is collected from Taipei City Hospital starting from 2008.1.1 to 2008.12.31. Based on the dataset, we first apply the sampling techniques and dimension reduction method to preprocess the testing data. Then, we construct various kinds of classifiers (including basic classifiers, ensemble methods, and cost-sensitive methods) to predict the risk. The cost-sensitive method with random forest classifier is able to achieve recall (or sensitivity) as 100 %. At the recall of 100 %, the precision (positive predictive value, PPV), and specificity of cost-sensitive method with random forest classifier was 2.9 % and 14.87 %, respectively. In our study, we build a breast cancer risk assessment model by using the data mining techniques. Our model has the potential to be served as an assisting tool in the breast cancer screening.
      pubtype: Academic Journal
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    language: English
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