An Imbalanced Learning based MDR-TB Early Warning System.

As a man-made disease, multidrug-resistant tuberculosis (MDR-TB) is mainly caused by improper treatment programs and poor patient supervision, most of which could be prevented. According to the daily treatment and inspection records of tuberculosis (TB) cases, this study focuses on establishing a wa...

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Publicado en:Journal of Medical Systems Vol. 40; no. 7; pp. 1 - 10
Autores principales: Li, Sheng, Tang, Bo, He, Haibo
Formato: equations & formulas research tables/charts Journal Article
Publicado: Springer Nature Jul2016
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Jul2016
      vid: 40
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      pub: Springer Nature
      place: New York, New York
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        atl: An Imbalanced Learning based MDR-TB Early Warning System.
      aug:
        au:
          Li, Sheng
          Tang, Bo
          He, Haibo
        affil: School of Information and Safety Engineering, Zhongnan University of Economics & Law, Wuhan China
      sug:
        subj:
          Tuberculosis, Multidrug-Resistant Risk Factors
          Algorithms
          Human
          China
          Record Review
          Infant, Newborn
          Infant
          Child
          Adolescence
          Adult
          Middle Age
          Aged
          Aged, 80 and Over
          Female
          Male
          ROC Curve
          False Positive Results
          Regression
          T-Tests
          Descriptive Statistics
          Infant, Newborn: birth-1 month
          Infant: 1-23 months
          Child: 6-12 years
          Adolescent: 13-18 years
          Adult: 19-44 years
          Middle Aged: 45-64 years
          Aged: 65+ years
          Aged, 80 & over
          Female
          Male
      ab: As a man-made disease, multidrug-resistant tuberculosis (MDR-TB) is mainly caused by improper treatment programs and poor patient supervision, most of which could be prevented. According to the daily treatment and inspection records of tuberculosis (TB) cases, this study focuses on establishing a warning system which could early evaluate the risk of TB patients converting to MDR-TB using machine learning methods. Different imbalanced sampling strategies and classification methods were compared due to the disparity between the number of TB cases and MDR-TB cases in historical data. The final results show that the relative optimal predictions results can be obtained by adopting CART-USBagg classification model in the first 90 days of half of a standardized treatment process.
      pubtype: Academic Journal
      doctype:
        equations & formulas
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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