Comparing Methods for Determining Motor-Hand Lateralization Based on fTCD Signals.

The lateralization index (LI) as determined from functional transcranial Doppler sonography (fTCD) can be used to determine the hemispheric organization of neural activation during a behavioral task. Previous studies have proposed different methods to determine this index, but to our knowledge no st...

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Published in:Journal of Medical Systems Vol. 39; no. 2; pp. 1 - 10
Main Authors: Pinaya, Walter, Fraga, Francisco, Haratz, Salo, Dean, Philip, Conforto, Adriana, Bor-Seng-Shu, Edson, Teixeira, Manoel, Sato, João
Format: equations & formulas pictorial research tables/charts tracings Journal Article
Published: Springer Nature Feb2015
Online Access:View this record in EBSCOhost
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      dt: Feb2015
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      pub: Springer Nature
      place: New York, New York
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        10.1007/s10916-014-0185-z
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        atl: Comparing Methods for Determining Motor-Hand Lateralization Based on fTCD Signals.
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          Pinaya, Walter
          Fraga, Francisco
          Haratz, Salo
          Dean, Philip
          Conforto, Adriana
          Bor-Seng-Shu, Edson
          Teixeira, Manoel
          Sato, João
        affil: Center for Engineering, Modeling and Applied Social Sciences, Universidade Federal do ABC, Rua Santa Adélia, 166 - Bairro Bangu Santo André CEP 09.210-170 Brazil
      sug:
        subj:
          Dominance, Cerebral Evaluation
          Ultrasonography, Doppler, Transcranial Methods
          Right-Handedness
          Human
          Task Performance and Analysis
          Clinical Assessment Tools
          Female
          Male
          Adult
          Middle Age
          Descriptive Statistics
          Spearman's Rank Correlation Coefficient
          Funding Source
          Adult: 19-44 years
          Middle Aged: 45-64 years
          Female
          Male
      ab: The lateralization index (LI) as determined from functional transcranial Doppler sonography (fTCD) can be used to determine the hemispheric organization of neural activation during a behavioral task. Previous studies have proposed different methods to determine this index, but to our knowledge no studies have compared the performance of these methods. In this study, we compare two established methods with a simpler method proposed here. The aim was to see whether similar results could be achieved with a simpler method and to give an indication of the analysis steps required to determine the LI. A simple unimanual motor task was performed while fTCD was acquired, and the LI determined by each of these methods was compared. In addition, LI determined by each method was related to behavioural output in the form of degree of handedness. The results suggest that although the methods differed in complexity, they yielded similar results when determining the lateralization of motor functions, and its correlation with behavior. Further investigation is needed to expand the conclusions of this preliminary study, however the new method proposed in the paper has great potential as it is much simpler than the more established methods yet yields similar results.
      pubtype: Academic Journal
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        equations & formulas
        pictorial
        research
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        Journal Article
      ougenre: Article
    language: English
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