Extraction of 3D Femur Neck Trabecular Bone Architecture from Clinical CT Images in Osteoporotic Evaluation: a Novel Framework.
The early detection of osteoporosis risk enhances the lifespan and quality of life of an individual. A reasonable in-vivo assessment of trabecular bone strength at the proximal femur helps to evaluate the fracture risk and henceforth, to understand the associated structural dynamics on occurrence of...
| Published in: | Journal of Medical Systems Vol. 39; no. 8; pp. 1 - 12 |
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| Main Authors: | , , |
| Format: | diagnostic images equations & formulas pictorial research tables/charts Journal Article |
| Published: |
Springer Nature
Aug2015
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| Online Access: | View this record in EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=115925516&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 115925516 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 01485598 4N0 jtl: Journal of Medical Systems issn: 01485598 maglogo: N pubinfo: dt: Aug2015 vid: 39 iid: 8 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 115925516 115925516 115925516 10.1007/s10916-015-0266-7 115925516 ppf: 1 ppct: 11 formats: fmt: @attributes: type: P tig: atl: Extraction of 3D Femur Neck Trabecular Bone Architecture from Clinical CT Images in Osteoporotic Evaluation: a Novel Framework. aug: au: Sapthagirivasan, V. Anburajan, M. Janarthanam, S. affil: Department of Biomedical Engineering, SRM University, Kattankalathur Chennai 603203 India sug: subj: Osteoporosis Risk Factors Cancellous Bone Anatomy and Histology Femur Neck Radiography Tomography, X-Ray Computed Imaging, Three-Dimensional Bone Density Evaluation Human Fractures Risk Factors India Female Confidence Intervals Absorptiometry, Photon Adult Middle Age Aged Aged, 80 and Over Cortical Bone Data Analysis Software Descriptive Statistics Pearson's Correlation Coefficient T-Tests In Vivo Studies Adult: 19-44 years Middle Aged: 45-64 years Aged: 65+ years Aged, 80 & over Female ab: The early detection of osteoporosis risk enhances the lifespan and quality of life of an individual. A reasonable in-vivo assessment of trabecular bone strength at the proximal femur helps to evaluate the fracture risk and henceforth, to understand the associated structural dynamics on occurrence of osteoporosis. The main aim of our study was to develop a framework to automatically determine the trabecular bone strength from clinical femur CT images and thereby to estimate its correlation with BMD. All the 50 studied south Indian female subjects aged 30 to 80 years underwent CT and DXA measurements at right femur region. Initially, the original CT slices were intensified and active contour model was utilised for the extraction of the neck region. After processing through a novel process called trabecular enrichment approach (TEA), the three dimensional (3D) trabecular features were extracted. The extracted 3D trabecular features, such as volume fraction ( VF), solidity of delta points ( SDP) and boundness, demonstrated a significant correlation with femoral neck bone mineral density ( r = 0.551, r = 0.432, r = 0.552 respectively) at p < 0.001. The higher area under the curve values of the extracted features ( VF: 85.3 %; 95CI: 68.2-100 %, SDP: 82.1 %; 95CI: 65.1-98.9 % and boundness: 90.4 %; 95CI: 78.7-100 %) were observed. The findings suggest that the proposed framework with TEA method would be useful for spotting women vulnerable to osteoporotic risk. pubtype: Academic Journal doctype: diagnostic images equations & formulas pictorial research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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