Abdominal fat distribution and carotid atherosclerosis in a general population: a semi-automated method using magnetic resonance imaging.
Purpose: Available evidence suggests functional differences in visceral and subcutaneous fat. We investigated the association between quantitative measures of central adiposity with indicators of carotid atherosclerosis including intima-media thickness (IMT) and plaque in a general population using...
| Publicado en: | Japanese Journal of Radiology Vol. 34; no. 6; pp. 414 - 423 |
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| Autores principales: | , , , , , , , , , , , , |
| Formato: | diagnostic images research tables/charts Journal Article |
| Publicado: |
Springer Nature
Jun2016
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=115930212&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 115930212 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 18671071 AUCM jtl: Japanese Journal of Radiology issn: 18671071 maglogo: N pubinfo: dt: Jun2016 vid: 34 iid: 6 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 115930212 115930212 NLM27015838 115930212 10.1007/s11604-016-0540-8 NLM27015838 115930212 ppf: 414 ppct: 9 formats: fmt: @attributes: type: P tig: atl: Abdominal fat distribution and carotid atherosclerosis in a general population: a semi-automated method using magnetic resonance imaging. aug: au: Radmard, Amir Poustchi, Hossein Ansari, Leila Khorasanizadeh, Faezeh Yoonessi, Ali Hashemi Taheri, Amir Rahmanian, Mohammad Jafari, Elham Malekzadeh, Reza Merat, Shahin Radmard, Amir Reza Hashemi Taheri, Amir Pejman Rahmanian, Mohammad Sadegh affil: Liver and Pancreatobiliary Diseases Research Center, Digestive Diseases Research Institute, Shariati Hospital, Tehran University of Medical Sciences, North Kargar St. Tehran 14117-13135 Iran sug: subj: Magnetic Resonance Imaging Methods Abdominal Fat Carotid Artery Diseases Reproducibility of Results Female Male Cross Sectional Studies Aged Carotid Intima-Media Thickness Middle Age Human Aged: 65+ years Middle Aged: 45-64 years Female Male ab: Purpose: Available evidence suggests functional differences in visceral and subcutaneous fat. We investigated the association between quantitative measures of central adiposity with indicators of carotid atherosclerosis including intima-media thickness (IMT) and plaque in a general population using a semi-automated method on magnetic resonance imaging (MRI) data.Methods: In this cross-sectional study 200 subjects (52 % female), aged 50-77 years, were randomly selected from Golestan Cohort Study. Participants underwent ultrasound examination of carotid arteries and abdominal MRI. Segmentation and calculation of visceral (VFA) and subcutaneous fat area (SFA) were performed on three levels using semi-automated software. Various conventional anthropometric indices were also measured.Results: Among 191 enrolled subjects, 77 (40 %) participants had IMT ≥0.8 mm. Carotid plaques were detected in 86 (44 %) subjects. In separate multivariate analysis models, unlike SFA and other anthropometric indices, the last tertile of VFA values was associated with at least threefold excess risk for IMT ≥0.8 mm (OR 3.8, 95 % CI 1.36-6.94, p = 0.02). There was no significant difference between mean values of categorized obesity indices in subjects with and without plaque, while participants in the highest tertile of VFA values were demonstrated to have higher risk of more than one plaque (OR 4.57, 95 % CI 1.03-20.11, p = 0.034).Conclusions: A higher amount of visceral fat, measured by a semi-automated technique using MRI, is associated with increased IMT and having more than one carotid plaque in a general population, while subcutaneous fat measures are poor indicators for identifying carotid atherosclerosis. pubtype: Academic Journal doctype: diagnostic images research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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