Test-retest reliability of high angular resolution diffusion imaging acquisition within medial temporal lobe connections assessed via tract based spatial statistics, probabilistic tractography and a novel graph theory metric.
This study examined the reliability of high angular resolution diffusion tensor imaging (HARDI) data collected on a single individual across several sessions using the same scanner. HARDI data was acquired for one healthy adult male at the same time of day on ten separate days across a one-month per...
| Publicado en: | Brain Imaging & Behavior Vol. 10; no. 2; pp. 533 - 548 |
|---|---|
| Autores principales: | , , , , , , , , , , , , , , , , , |
| Formato: | diagnostic images equations & formulas research tables/charts Journal Article |
| Publicado: |
Springer Nature
Jun2016
|
| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=116148049&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 116148049 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 19317557 3GSC jtl: Brain Imaging & Behavior issn: 19317557 maglogo: N pubinfo: dt: Jun2016 vid: 10 iid: 2 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 116148049 116148049 NLM26189060 116148049 10.1007/s11682-015-9425-1 NLM26189060 PMC4718901 116148049 ppf: 533 ppct: 15 formats: fmt: @attributes: type: P tig: atl: Test-retest reliability of high angular resolution diffusion imaging acquisition within medial temporal lobe connections assessed via tract based spatial statistics, probabilistic tractography and a novel graph theory metric. aug: au: Kuhn, T. Gullett, J. Nguyen, P. Boutzoukas, A. Ford, A. Colon-Perez, L. Triplett, W. Carney, P. Mareci, T. Price, C. Bauer, R. Gullett, J M Boutzoukas, A E Colon-Perez, L M Carney, P R Mareci, T H Price, C C Bauer, R M affil: Department of Clinical and Health Psychology, University of Florida, Gainesville 32610 USA sug: subj: Magnetic Resonance Imaging Methods Reproducibility of Results Image Processing, Computer Assisted Methods Brain Physiology Adult Image Processing, Computer Assisted Magnetic Resonance Imaging Statistics and Numerical Data Temporal Lobe Physiology Male Human Funding Source Adult: 19-44 years Male ab: This study examined the reliability of high angular resolution diffusion tensor imaging (HARDI) data collected on a single individual across several sessions using the same scanner. HARDI data was acquired for one healthy adult male at the same time of day on ten separate days across a one-month period. Environmental factors (e.g. temperature) were controlled across scanning sessions. Tract Based Spatial Statistics (TBSS) was used to assess session-to-session variability in measures of diffusion, fractional anisotropy (FA) and mean diffusivity (MD). To address reliability within specific structures of the medial temporal lobe (MTL; the focus of an ongoing investigation), probabilistic tractography segmented the Entorhinal cortex (ERc) based on connections with Hippocampus (HC), Perirhinal (PRc) and Parahippocampal (PHc) cortices. Streamline tractography generated edge weight (EW) metrics for the aforementioned ERc connections and, as comparison regions, connections between left and right rostral and caudal anterior cingulate cortex (ACC). Coefficients of variation (CoV) were derived for the surface area and volumes of these ERc connectivity-defined regions (CDR) and for EW across all ten scans, expecting that scan-to-scan reliability would yield low CoVs. TBSS revealed no significant variation in FA or MD across scanning sessions. Probabilistic tractography successfully reproduced histologically-verified adjacent medial temporal lobe circuits. Tractography-derived metrics displayed larger ranges of scanner-to-scanner variability. Connections involving HC displayed greater variability than metrics of connection between other investigated regions. By confirming the test retest reliability of HARDI data acquisition, support for the validity of significant results derived from diffusion data can be obtained. pubtype: Academic Journal doctype: diagnostic images equations & formulas research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
|---|