Pyoderma Gangrenosum.

The aim of this study was to document the profile of pyoderma gangrenosum (PG) patients who were treated in our clinic and to compare our patients’ clinical and demographic characteristics with those described in the literature to help our understanding of the total burden of PG. A total of 27 (17 w...

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Publicado en:International Journal of Lower Extremity Wounds Vol. 15; no. 2; pp. 148 - 155
Autores principales: Adışen, Esra, Erduran, Funda, Gürer, Mehmet Ali
Formato: pictorial research tables/charts Journal Article
Publicado: Sage Publications Inc. Jun2016
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Jun2016
      vid: 15
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      pub: Sage Publications Inc.
      place: Thousand Oaks, California
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        10.1177/1534734616639172
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        atl: Pyoderma Gangrenosum.
      aug:
        au:
          Adışen, Esra
          Erduran, Funda
          Gürer, Mehmet Ali
        affil: Gazi University, Ankara, Turkey.
      sug:
        subj:
          Pyoderma Gangrenosum Drug Therapy
          Human
          Outpatient Service
          Demography
          Male
          Female
          Middle Age
          Lower Extremity Pathology
          Length of Stay
          Adrenal Cortex Hormones Therapeutic Use
          Pyoderma Gangrenosum Mortality
          Readmission
          Pyoderma Gangrenosum Economics
          Middle Aged: 45-64 years
          Male
          Female
      ab: The aim of this study was to document the profile of pyoderma gangrenosum (PG) patients who were treated in our clinic and to compare our patients’ clinical and demographic characteristics with those described in the literature to help our understanding of the total burden of PG. A total of 27 (17 women, 10 men) patients with a mean age 48.6 years at diagnosis were included in the study. Seven (25.9%) of them had 3 or more ulcers. The lower extremity was the most common site of occurrence (92.5%). During the study period, 6 patients were admitted twice, and 7 were admitted 3 or more times (range 1 to >10), and the median length of stay was 27 days. A concomitant disease was present in PG patients especially in those between 20 and 40 years of age. Systemic therapy was used in 21 (91.3%) patients, 17 patients were treated with systemic corticosteroids, either alone in 7 patients or combination with other agents in 10 patients. Three of our patients died because of disease or treatment-related complications during the study period. Despite the high (70.3%) percentage of the PG patients with improving disease at the time of discharge, 1 year after hospital discharge, one third of our 27 patients still had PG requiring readmission. In conclusion, none of the current therapies provide satisfying results in all of the patients, and our data indicate a long-standing unmet need for effective therapy for the unexpected course of PG.
      pubtype: Academic Journal
      doctype:
        pictorial
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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