Nasal mucocutaneous cryptococcosis: a case report.

A 47-year-old woman, carrier systemic hypertension, tobacco user, and chronic user of corticosteroids, showed skin and nasal mucosa lesions, with local pain; treated empirically as sinusitis. The lesions evolved with increased ulceration. After nine months of symptoms onset, the lesion was biopsied,...

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Detalles Bibliográficos
Publicado en:	Revista Panamericana de Infectología Vol. 16; no. 1; pp. 67 - 71
Autores principales:	Sonda, Eduardo Chaida, Chaves, William Scheffer, Scheid, Rafaela, Pereira, Luciane Mattos, Donaduzzi, Thaís, Krumel, Candice Franke, Hernandes Machado, Cristiane Pimentel
Formato:	Case Study
Publicado:	Asociacion Panamericana de Infectologia 2014
Materias:	Cryptococcosis Diagnosis of HIV infections Fluconazole
Acceso en línea:	Ver este registro en EBSCOhost

Descripción
Sumario:	A 47-year-old woman, carrier systemic hypertension, tobacco user, and chronic user of corticosteroids, showed skin and nasal mucosa lesions, with local pain; treated empirically as sinusitis. The lesions evolved with increased ulceration. After nine months of symptoms onset, the lesion was biopsied, revealing fungal skin pathology suggestive of cryptococcosis. The patient was diagnosed with an HIV infection. The patient was then hospitalized in a specialized hospital and treated with intravenous fluconazole 800mg/day, followed by fluconazole 800mg daily orally up to 12 weeks of treatment. There was resolution of the ulcerated lesion and subsequent fibrosis of the left nostril. Paciente feminina, 47 anos, hipertensa e tabagista, em uso crônico de corticoide, apresentou lesões em pele e mucosa nasal, com dor local; tratado empiricamente como sinusite. Houve piora das lesões, com ulceração. Após nove meses do início dos sintomas, foi realizada biópsia da lesão, revelando o anatomopatológico uma micose cutânea sugestiva de criptococose. A paciente foi diagnosticada com infecção pelo vírus da imunodeficiência humana (HIV) e, então, internada em hospital de referência, tendo recebido tratamento com fluconazol 800mg/dia endovenoso, a seguir, fluconazol 800mg/dia oral até completar 12 semanas de tratamento. Houve resolução da lesão ulcerada e posterior fibrose da narina esquerda.