The association between pre-treatment occupational skill level and mood and symptom burden in early-stage, postmenopausal breast cancer survivors during the first year of anastrozole therapy.

Purpose: Previous research has explored occupational activity of breast cancer survivors but has not examined the influence of occupational level on symptoms prospectively. The purpose of this study was to examine the relationship between occupational classification and changes in mood and symptom b...

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Publicado en:Supportive Care in Cancer Vol. 24; no. 8; pp. 3401 - 3410
Autores principales: Nugent, Bethany, Sereika, Susan, Rosenzweig, Margaret, McCue, Michael, Merriman, John, Bender, Catherine, Nugent, Bethany D, Sereika, Susan M, Merriman, John D, Bender, Catherine M
Formato: research tables/charts Journal Article
Publicado: Springer Nature Aug2016
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Aug2016
      vid: 24
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      pub: Springer Nature
      place: New York, New York
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        atl: The association between pre-treatment occupational skill level and mood and symptom burden in early-stage, postmenopausal breast cancer survivors during the first year of anastrozole therapy.
      aug:
        au:
          Nugent, Bethany
          Sereika, Susan
          Rosenzweig, Margaret
          McCue, Michael
          Merriman, John
          Bender, Catherine
          Nugent, Bethany D
          Sereika, Susan M
          Merriman, John D
          Bender, Catherine M
        affil: School of Nursing, University of Pittsburgh, 415 Victoria Bldg., 3500 Victoria St. Pittsburgh 15261 USA
      sug:
        subj:
          Heterocyclic Compounds Therapeutic Use
          Antineoplastic Agents, Hormonal Therapeutic Use
          Organic Chemicals Therapeutic Use
          Breast Neoplasms Complications
          Employment
          Middle Age
          Survivors
          Affect
          Heterocyclic Compounds Pharmacodynamics
          Breast Neoplasms Drug Therapy
          Postmenopause
          Breast Neoplasms Mortality
          Female
          Organic Chemicals Pharmacodynamics
          Cognition
          Antineoplastic Agents, Hormonal Pharmacodynamics
          Heterocyclic Compounds Administration and Dosage
          Organic Chemicals Administration and Dosage
          Antineoplastic Agents, Hormonal Administration and Dosage
          Self Report
          Funding Source
          Human
          Middle Aged: 45-64 years
          Female
      ab: Purpose: Previous research has explored occupational activity of breast cancer survivors but has not examined the influence of occupational level on symptoms prospectively. The purpose of this study was to examine the relationship between occupational classification and changes in mood and symptom burden for postmenopausal breast cancer survivors during the first year of anastrozole therapy.Methods: This was an exploratory secondary analysis in 49 postmenopausal women receiving anastrozole therapy for early-stage breast cancer. Participants reported their occupation at baseline and completed self-report questionnaires measuring mood and symptom burden at baseline, 6 months, and 12 months. Occupation was classified according to four major skill levels delineated by the International Standard Classification of Occupations (ISCO).Results: Breast cancer survivors employed at occupational skill levels 1 through 3 reported significantly higher depressive symptoms, fatigue, and total symptoms on average than those employed at ISCO skill level 4. After adjusting for multiple comparisons, this pattern remained for the musculoskeletal, vasomotor, and gastrointestinal symptom subscales.Conclusions: Breast cancer survivors employed at lower skill levels (i.e., ISCO 1-3) reported poorer mood and greater symptom burden than breast cancer survivors employed at a higher skill level (i.e., ISCO 4). Assessing baseline occupation of occupationally active breast cancer survivors may improve understanding of the association between types of occupations and mood and symptom trajectories and may inform development of interventions to mitigate symptom severity in order to help breast cancer survivors maintain optimal occupational function and adherence to therapy.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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