Lymph vessels: the forgotten second circulation in health and disease.

The lymphatic circulation is still a somewhat forgotten part of the circulatory system. Despite this, novel insights in lymph angiogenesis in health and disease, application of immune markers for lymphatic growth and differentiation and also the introduction of new imaging techniques to visualize th...

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Publicado en:Virchows Archiv: European Journal of Pathology Vol. 469; no. 1; pp. 3 - 18
Autores principales: Adamczyk, Lukasz, Gordon, Kristiana, Kholová, Ivana, Meijer-Jorna, Lorine, Telinius, Niklas, Gallagher, Patrick, Wal, Allard, Baandrup, Ulrik, Adamczyk, Lukasz A, Meijer-Jorna, Lorine B, Gallagher, Patrick J, van der Wal, Allard C
Formato: review Journal Article
Publicado: Springer Nature Jul2016
Acceso en línea:Ver este registro en EBSCOhost
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        atl: Lymph vessels: the forgotten second circulation in health and disease.
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        au:
          Adamczyk, Lukasz
          Gordon, Kristiana
          Kholová, Ivana
          Meijer-Jorna, Lorine
          Telinius, Niklas
          Gallagher, Patrick
          Wal, Allard
          Baandrup, Ulrik
          Adamczyk, Lukasz A
          Kholová, Ivana
          Meijer-Jorna, Lorine B
          Gallagher, Patrick J
          van der Wal, Allard C
        affil: North Bristol NHS Trust, Bristol UK
      sug:
        subj:
          Endothelium Pathology
          Fetal Development Immunology
          Lymphatic System Pathology
          Proteins Metabolism
          Endothelium Immunology
          Lymphatic System Immunology
          Membrane Proteins Metabolism
          Endothelium Metabolism
          Animals
      ab: The lymphatic circulation is still a somewhat forgotten part of the circulatory system. Despite this, novel insights in lymph angiogenesis in health and disease, application of immune markers for lymphatic growth and differentiation and also the introduction of new imaging techniques to visualize the lymphatic circulation have improved our understanding of lymphatic function in both health and disease, especially in the last decade. These achievements yield better understanding of the various manifestations of lymph oedemas and malformations, and also the patterns of lymphovascular spread of cancers. Immune markers that recognize lymphatic endothelium antigens, such as podoplanin, LYVE-1 and Prox-1, can be successfully applied in diagnostic pathology and have revealed (at least partial) lymphatic differentiation in many types of vascular lesions.
      pubtype: Academic Journal
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        review
        Journal Article
      ougenre: Article
    language: English
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