Comparison between two-dimensional synthetic mammography reconstructed from digital breast tomosynthesis and full-field digital mammography for the detection of T1 breast cancer.

Objective: To evaluate the interpretative performance of two-dimensional (2D) synthetic mammography (SM) reconstructed from digital breast tomosynthesis (DBT) in the detection of T1-stage invasive breast cancers, compared to 2D full-field digital mammography (FFDM).Methods: This retrospective study...

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Publicado en:European Radiology Vol. 26; no. 8; pp. 2538 - 2547
Autores principales: Choi, Ji, Han, Boo-Kyung, Ko, Eun, Hahn, Soo, Shin, Jung, Kim, Min, Choi, Ji Soo, Ko, Eun Young, Ko, Eun Sook, Hahn, Soo Yeon, Shin, Jung Hee, Kim, Min Jung
Formato: research Journal Article
Publicado: Springer Nature Aug2016
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Aug2016
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      pub: Springer Nature
      place: New York, New York
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        atl: Comparison between two-dimensional synthetic mammography reconstructed from digital breast tomosynthesis and full-field digital mammography for the detection of T1 breast cancer.
      aug:
        au:
          Choi, Ji
          Han, Boo-Kyung
          Ko, Eun
          Hahn, Soo
          Shin, Jung
          Kim, Min
          Choi, Ji Soo
          Ko, Eun Young
          Ko, Eun Sook
          Hahn, Soo Yeon
          Shin, Jung Hee
          Kim, Min Jung
        affil: Department of Radiology, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-Ro Gangnam-gu Seoul 135-710 South Korea
      sug:
        subj:
          Radiographic Image Enhancement Methods
          Tomography, X-Ray Computed Methods
          Mammography Methods
          Breast Neoplasms
          Middle Age
          Female
          Human
          Aged
          Reproducibility of Results
          Retrospective Design
          ROC Curve
          Adult
          Validation Studies
          Comparative Studies
          Evaluation Research
          Multicenter Studies
          Middle Aged: 45-64 years
          Aged: 65+ years
          Adult: 19-44 years
          Female
      ab: Objective: To evaluate the interpretative performance of two-dimensional (2D) synthetic mammography (SM) reconstructed from digital breast tomosynthesis (DBT) in the detection of T1-stage invasive breast cancers, compared to 2D full-field digital mammography (FFDM).Methods: This retrospective study enrolled 214 patients. For each patient, FFDM and DBT were performed between January and June 2013, and SM was reconstructed from DBT data. Three radiologists interpreted images and recorded visibility scores and morphologies of cancers. Diagnostic performances of SM and FFDM were compared. Percentages of detected cancers and visibility scores were compared for tumour size, and presence of calcifications for each observer.Results: Observer sensitivity showed no difference for detection with SM and FFDM (P > 0.05). One observer showed a higher specificity (P = 0.02) and higher positive predictive value with SM (95 % CI 0.6-16.4), but the differences in the corresponding values between SM and FFDM for the other observers were not statistically significant. In subgroup analyses according to tumour size and presence of calcifications, percentages of detected cancers and visibility scores were not significantly different.Conclusions: Diagnostic performances of SM and FFDM are comparable for detecting T1-stage breast cancers. Therefore, our results indicate that SM may eliminate the need for additional FFDM during DBT-based imaging.Key Points: • DBT plus FFDM increases radiation dose compared to FFDM alone. • Detecting T1-stage cancers with only SM is comparable to detection with FFDM. • Two-dimensional SM may replace dose-requiring FFDM in DBT-based imaging.
      pubtype: Academic Journal
      doctype:
        research
        Journal Article
      ougenre: Article
    language: English
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