Reducing ICD Test Shocks with a Simplified Upper Limit of Vulnerability.

Background Determination of an adequate defibrillation safety margin or defibrillation threshold can be a challenge in patients with implantable defibrillators (ICDs). The upper limit of vulnerability (ULV) has been shown to be highly correlated with measured defibrillation thresholds. The peak of t...

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Publicado en:Pacing & Clinical Electrophysiology Vol. 39; no. 7; pp. 652 - 658
Autores principales: PITTARO, MICHAEL, DEFORGE, WILLIAM, KROLL, MARK W.
Formato: algorithm research tables/charts tracings Journal Article
Publicado: Wiley-Blackwell Jul2016
Acceso en línea:Ver este registro en EBSCOhost
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        atl: Reducing ICD Test Shocks with a Simplified Upper Limit of Vulnerability.
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          PITTARO, MICHAEL
          DEFORGE, WILLIAM
          KROLL, MARK W.
        affil: Norwalk Hospital, Norwalk Connecticut
      sug:
        subj:
          Defibrillators, Implantable Evaluation
          Cardiac Resynchronization Therapy Equipment and Supplies
          Cardiac Patients Statistics and Numerical Data
          Human
          Electrocardiography
          Algorithms
          Male
          Female
          Middle Age
          Aged
          Aged, 80 and Over
          Adult
          T-Tests
          Descriptive Statistics
          Data Analysis Software
          Middle Aged: 45-64 years
          Aged: 65+ years
          Aged, 80 & over
          Adult: 19-44 years
          Male
          Female
      ab: Background Determination of an adequate defibrillation safety margin or defibrillation threshold can be a challenge in patients with implantable defibrillators (ICDs). The upper limit of vulnerability (ULV) has been shown to be highly correlated with measured defibrillation thresholds. The peak of the latest peaking monophasic T wave measured from the pacing spike of the induction train of S1 via the surface electrocardiogram (ECG) is generally accepted to approximate the vulnerable period of the cardiac cycle. Objectives The purpose of this study was to determine whether a single electrogram-derived coupling interval could provide an accurate determination of the vulnerable period for a simplified test method to approximate the defibrillation safety margin. Methods We used a single electrogram-derived coupling interval for the timing of the T shock. We compared the measured intracardiac electrogram coupling interval to the latest peaking T wave on the surface ECG. Results A total of 72 patients were studied: single-chamber ICD (n = 28), dual-chamber ICD (n = 26), or cardiac resynchronization therapy-defibrillator (n = 18). The coupling intervals were greater on the electrograms versus the surface ECG: 365 ms ± 27 versus 347 ms ± 26 (P < 0.0001). Almost all of the patients tested, 69/72 (96%), were indeed defibrillated with the T-shock energy that failed to induce ventricular fibrillation (VF). Only three (4%) of the patients failed the hypothesis when 500 V failed to induce VF but subsequently also failed to defibrillate a forced induction of VF. Conclusions A simplified ULV testing protocol, using a single electrogram channel, accurately separates low from high defibrillation threshold testing patients.
      pubtype: Academic Journal
      doctype:
        algorithm
        research
        tables/charts
        tracings
        Journal Article
      ougenre: Article
    language: English
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