Continuous subcutaneous glucose monitoring is accurate in term and near-term infants at risk of hypoglycaemia.
Aim: Postnatal hypoglycaemia increases the risk of adverse neurological outcomes in newborn infants, and adequate glucose control requires repetitive and painful blood sampling. This study evaluated a continuous glucose monitoring system (CGMS) that aims to improve glucose control and decrease the f...
| Publicado en: | Acta Paediatrica Vol. 105; no. 8; pp. 917 - 924 |
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| Autores principales: | , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Wiley-Blackwell
Aug2016
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=116645648&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 116645648 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 08035253 44C jtl: Acta Paediatrica issn: 08035253 maglogo: Y pubinfo: dt: Aug2016 vid: 105 iid: 8 pid: 480 pub: Wiley-Blackwell place: Malden, Massachusetts artinfo: ui: 116645648 116645648 NLM27203555 116645648 10.1111/apa.13479 NLM27203555 116645648 ppf: 917 ppct: 7 formats: tig: atl: Continuous subcutaneous glucose monitoring is accurate in term and near-term infants at risk of hypoglycaemia. aug: au: Wackernagel, Dirk Dube, Martina Blennow, Mats Tindberg, Ylva affil: Centre for Clinical Research, Sörmland, Uppsala University, Uppsala Sweden sug: subj: Blood Glucose Analysis Infant, Newborn, Diseases Diagnosis Hypoglycemia Diagnosis Infant, Newborn Monitoring, Physiologic Methods Infant, Premature Human Infant, Newborn: birth-1 month ab: Aim: Postnatal hypoglycaemia increases the risk of adverse neurological outcomes in newborn infants, and adequate glucose control requires repetitive and painful blood sampling. This study evaluated a continuous glucose monitoring system (CGMS) that aims to improve glucose control and decrease the frequency of blood samples taken from neonates.Methods: CGMS sensors, which measure glucose values every five minutes and require calibration twice a day, were placed on 20 infants at risk of hypoglycaemia. The infants also underwent blood glucose sampling, and the blood glucose values were compared with CGMS values six times during the first 30 minutes after sampling.Results: We used 97/264 (37%) of the blood glucose values taken for the CGMS calibration. The highest accuracy, a mean of 0.22 (95% confidence interval 0.13-0.30 mmol/L), was found 15-19 minutes after sampling, due to the calibration process. No significant subcutaneous glucose time lag was detectable.Conclusion: The CGMS system was an accurate and feasible method for glucose control, provided earlier detection of hypoglycaemia in newborn infants and reduced their exposure to procedural pain. The delay in calibration in infants was a new finding and needs to be taken into account when comparing CGMS readings to blood glucose values. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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