No effects of pantoprazole on the pharmacokinetics of rosuvastatin in healthy subjects.

Purpose: Rosuvastatin disposition is modulated by the expression and activity of several membrane transporters including BCRP (ABCG2). The objective of our study was to investigate the effects of pantoprazole, a previously proposed BCRP inhibitor, on the disposition of rosuvastatin. Methods: The imp...

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Bibliographic Details

Published in:	European Journal of Clinical Pharmacology Vol. 72; no. 8; pp. 925 - 932
Main Authors:	Huguet, J., Lu, J., Gaudette, F., Chiasson, J.-L., Hamet, P., Michaud, V., Turgeon, J.
Format:	clinical trial equations & formulas research tables/charts Journal Article
Published:	Springer Nature Aug2016
Online Access:	View this record in EBSCOhost