Resistant starch for modulation of gut microbiota: Promising adjuvant therapy for chronic kidney disease patients?

The gut microbiota has been extensively studied in all health science fields because its imbalance is linked to many disorders, such as inflammation and oxidative stress, thereby contributing to cardiovascular disease, obesity, diabetes and chronic kidney disease (CKD) complications. Novel therapeut...

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Publicado en:European Journal of Nutrition Vol. 55; no. 5; pp. 1813 - 1822
Autores principales: Moraes, Cristiane, Borges, Natália, Mafra, Denise
Formato: review tables/charts Journal Article
Publicado: Springer Nature Aug2016
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Aug2016
      vid: 55
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      pub: Springer Nature
      place: New York, New York
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        10.1007/s00394-015-1138-0
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        atl: Resistant starch for modulation of gut microbiota: Promising adjuvant therapy for chronic kidney disease patients?
      aug:
        au:
          Moraes, Cristiane
          Borges, Natália
          Mafra, Denise
        affil: Graduate Program in Cardiovascular Sciences, Fluminense Federal University (UFF), Niterói Brazil
      sug:
        subj:
          Microbiota
          Stomach Microbiology
          Prebiotics Therapeutic Use
          Glucans Therapeutic Use
          Renal Insufficiency, Chronic Therapy
          Glucans Physiology
          Renal Insufficiency, Chronic Metabolism
          Nitrogen Urine
          Fermentation
          Dietary Fiber Administration and Dosage
          Fatty Acids Metabolism
          Glucans Metabolism
      ab: The gut microbiota has been extensively studied in all health science fields because its imbalance is linked to many disorders, such as inflammation and oxidative stress, thereby contributing to cardiovascular disease, obesity, diabetes and chronic kidney disease (CKD) complications. Novel therapeutic strategies that aim to reduce the complications caused by this imbalance have increased in recent years. Studies have shown that prebiotic supplementation can beneficially modulate the gut microbiota in CKD patients. Prebiotics consist of non-digestible dietary soluble fiber, which acts as a substrate for the gut microbiota. Resistant starch (RS) is a type of dietary fiber that can reach the large bowel and act as a substrate for microbial fermentation; for these reasons, it has been considered to be a prebiotic. Few studies have analyzed the effects of RS on the gut microbiota in CKD patients. This review discusses recent information about RS and the potential role of the gut microbiota, with a particular emphasis on CKD patients.
      pubtype: Academic Journal
      doctype:
        review
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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