Prevalence of impaired glucose regulation in Europe: a meta-analysis.

Background: Impaired glucose regulation represents an opportunity to prevent Type 2 diabetes mellitus. It is important to have a clear understanding of the prevalence of this condition in order to be able to plan interventions and health care provision. This paper presents a meta-analysis of literat...

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Published in:European Journal of Public Health Vol. 26; no. 4; pp. 699 - 707
Main Authors: Eades, Claire E., France, Emma F., Evans, Josie M. M.
Format: meta analysis research tables/charts Journal Article
Published: Oxford University Press / USA Aug2016
Online Access:View this record in EBSCOhost
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      dt: Aug2016
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      pub: Oxford University Press / USA
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        10.1093/eurpub/ckw085
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        atl: Prevalence of impaired glucose regulation in Europe: a meta-analysis.
      aug:
        au:
          Eades, Claire E.
          France, Emma F.
          Evans, Josie M. M.
        affil: Faculty of Health Sciences and Sport, University of Stirling, Stirling, UK
      sug:
        subj:
          Glycemic Control Europe
          Prediabetic State Epidemiology
          Human
          Meta Analysis
          Europe
          Descriptive Statistics
          Medline
          Embase
          CINAHL Database
          Research Methodology Evaluation
          Checklists
          Effect Size
          Adult
          Middle Age
          Aged
          Confidence Intervals
          Geographic Factors
          Male
          Female
          Multiple Regression
          Multivariate Analysis
          Sex Factors
          Adult: 19-44 years
          Middle Aged: 45-64 years
          Aged: 65+ years
          Male
          Female
      ab: Background: Impaired glucose regulation represents an opportunity to prevent Type 2 diabetes mellitus. It is important to have a clear understanding of the prevalence of this condition in order to be able to plan interventions and health care provision. This paper presents a meta-analysis of literature assessing the prevalence of impaired glucose regulation in the general population of developed countries in Europe. Methods: Five electronic databases were systematically searched in March 2014 to identify English language articles with general population samples aged 18 and over from developed countries in Europe. Values for the measures of interest were combined using a random effects model and analysis of the effects of moderator variables was carried out. Results: A total of 5594 abstracts were screened, with 46 studies included in the review. Overall prevalence of impaired glucose regulation was 22.3%. Mean prevalence of impaired glucose tolerance was 11.4% (10.1-12.8) and did not differ by gender. Sample age, diagnostic criteria and country were found to have a significant univariate effect on prevalence of impaired glucose tolerance but only diagnostic criteria remained significant in multivariate analysis. Mean prevalence of impaired fasting glucose was significantly higher in men at 10.1% (7.9-12.7) compared with 5.9% in women (4-8.7). The only moderator variable with a significant effect on impaired fasting glucose prevalence was country. Conclusions: This meta-analysis shows a moderate prevalence of impaired glucose regulation in developed Europe with over one in five people meeting the criteria for either impaired glucose tolerance, impaired fasting glucose or both.
      pubtype: Academic Journal
      doctype:
        meta analysis
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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