Facing competition: Neural mechanisms underlying parallel programming of antisaccades and prosaccades.

The antisaccade task is a prominent tool to investigate the response inhibition component of cognitive control. Recent theoretical accounts explain performance in terms of parallel programming of exogenous and endogenous saccades, linked to the horse race metaphor. Previous studies have tested the h...

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Publicado en:Brain & Cognition Vol. 107; pp. 37 - 48
Autores principales: Talanow, Tobias, Kasparbauer, Anna-Maria, Steffens, Maria, Meyhöfer, Inga, Weber, Bernd, Smyrnis, Nikolaos, Ettinger, Ulrich
Formato: research Journal Article
Publicado: Academic Press Inc. Aug2016
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Aug2016
      vid: 107
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      pub: Academic Press Inc.
      place: Burlington, Massachusetts
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        10.1016/j.bandc.2016.05.006
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        atl: Facing competition: Neural mechanisms underlying parallel programming of antisaccades and prosaccades.
      aug:
        au:
          Talanow, Tobias
          Kasparbauer, Anna-Maria
          Steffens, Maria
          Meyhöfer, Inga
          Weber, Bernd
          Smyrnis, Nikolaos
          Ettinger, Ulrich
        affil: Department of Psychology, University of Bonn, Bonn, Germany
      sug:
        subj:
          Magnetic Resonance Imaging
          Executive Function
          Cerebral Cortex Physiology
          Behavior
          Psychomotor Performance
          Eye Movements Physiology
          Male
          Young Adult
          Saccades Physiology
          Eye Movement Measurements
          Female
          Adult
          Human
          Adult: 19-44 years
          Male
          Female
      ab: The antisaccade task is a prominent tool to investigate the response inhibition component of cognitive control. Recent theoretical accounts explain performance in terms of parallel programming of exogenous and endogenous saccades, linked to the horse race metaphor. Previous studies have tested the hypothesis of competing saccade signals at the behavioral level by selectively slowing the programming of endogenous or exogenous processes e.g. by manipulating the probability of antisaccades in an experimental block. To gain a better understanding of inhibitory control processes in parallel saccade programming, we analyzed task-related eye movements and blood oxygenation level dependent (BOLD) responses obtained using functional magnetic resonance imaging (fMRI) at 3T from 16 healthy participants in a mixed antisaccade and prosaccade task. The frequency of antisaccade trials was manipulated across blocks of high (75%) and low (25%) antisaccade frequency. In blocks with high antisaccade frequency, antisaccade latencies were shorter and error rates lower whilst prosaccade latencies were longer and error rates were higher. At the level of BOLD, activations in the task-related saccade network (left inferior parietal lobe, right inferior parietal sulcus, left precentral gyrus reaching into left middle frontal gyrus and inferior frontal junction) and deactivations in components of the default mode network (bilateral temporal cortex, ventromedial prefrontal cortex) compensated increased cognitive control demands. These findings illustrate context dependent mechanisms underlying the coordination of competing decision signals in volitional gaze control.
      pubtype: Academic Journal
      doctype:
        research
        Journal Article
      ougenre: Article
    language: English
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