Hyperbaric Oxygen Therapy for the Adjunctive Treatment of Pyoderma Gangrenosum: A Case Report.

Pyoderma gangrenosum (PG) is a neutrophilic dermatosis of unknown etiology characterized by an ulcerative skin condition and confirmed through a diagnosis of exclusion. Management usually consists of systemic drug therapy, such as corticosteroids, sulfones, or immunosuppressants, either alone or in...

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Publicado en:Ostomy Wound Management Vol. 62; no. 5; pp. 32 - 36
Autores principales: l-Han Chiang, Yi-Shu Liao, Niann-Tzyy Dai, Hao-Yu Chiao, Chang-Yi Chou, Shyi-Gen Chen, Tim-Mo Chen, Shun-Cheng Chang
Formato: case study pictorial Journal Article
Publicado: HMP Global May2016
Acceso en línea:Ver este registro en EBSCOhost
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      dt: May2016
      vid: 62
      iid: 5
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      pub: HMP Global
      place: Malvern, Pennsylvania
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        atl: Hyperbaric Oxygen Therapy for the Adjunctive Treatment of Pyoderma Gangrenosum: A Case Report.
      aug:
        au:
          l-Han Chiang
          Yi-Shu Liao
          Niann-Tzyy Dai
          Hao-Yu Chiao
          Chang-Yi Chou
          Shyi-Gen Chen
          Tim-Mo Chen
          Shun-Cheng Chang
        affil: Plastic resident, Division of Plastic Surgery, Department of Surgery, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan, Republic of China
      sug:
        subj:
          Hyperbaric Oxygenation
          Pyoderma Gangrenosum Therapy
          Wound Care Methods
          Female
          Middle Age
          Ulcer Etiology
          Pyoderma Gangrenosum Diagnosis
          Prednisone Administration and Dosage
          Wound Healing
          Treatment Outcomes
          Middle Aged: 45-64 years
          Female
      ab: Pyoderma gangrenosum (PG) is a neutrophilic dermatosis of unknown etiology characterized by an ulcerative skin condition and confirmed through a diagnosis of exclusion. Management usually consists of systemic drug therapy, such as corticosteroids, sulfones, or immunosuppressants, either alone or in combination. Long-term use of these medications often has untold side effects. Hyperbaric oxygen therapy (HBOT) has been shown effective in the treatment of PG, reducing pain and tempering the need for medication. A case is presented of a 54-year-old woman with diabetes, hypertension, and a peptic ulcer who presented with painful, purulent ulcers on her buttocks, hands, and lower extremities of 2 weeks' duration. She was ultimately diagnosed with PG and provided 20 mg/day of oral prednisone for 1 week, tapered to 10 mg/day in the next week and then stopped. In addition, she received 12 sessions of HBOT — she breathed in 100% oxygen under 2.5 atmospheres absolute pressure for 90 minutes over 2 weeks. Her wounds healed without scarring. This excellent outcome including good wound healing, decreased pain, and reduced doses of systemic corticosteroids warrants additional study of the adjunctive use of HBOT for PG.
      pubtype: Academic Journal
      doctype:
        case study
        pictorial
        Journal Article
      ougenre: Article
    language: English
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