Factors Influencing Cognitive Function in Subjects With COPD.

BACKGROUND: The aim of this study was to assess the association between cognitive function and age, pulmonary function, comorbidity index, and the 6-min walk distance in subjects with COPD as well as to compare the Mini Mental State Examination (MMSE) and Montreal Cognitive Assessment (MoCA) in term...

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Publicado en:Respiratory Care Vol. 61; no. 8; pp. 1044 - 1051
Autores principales: Dag, Ersel, Bulcun, Emel, Turkel, Yakup, Ekici, Aydanur, Ekici, Mehmet
Formato: research tables/charts Journal Article
Publicado: Mary Ann Liebert, Inc. Aug2016
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Aug2016
      vid: 61
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      pub: Mary Ann Liebert, Inc.
      place: New Rochelle, New York
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        atl: Factors Influencing Cognitive Function in Subjects With COPD.
      aug:
        au:
          Dag, Ersel
          Bulcun, Emel
          Turkel, Yakup
          Ekici, Aydanur
          Ekici, Mehmet
        affil: Department of Neurology, Kırıkkale University Faculty of Medicine, Kırıkkale, Turkey
      sug:
        subj:
          Pulmonary Disease, Chronic Obstructive
          Cognition
          Human
          Scales
          Comorbidity
          Blood Gas Analysis
          Respiratory Function Tests
          Cognition Evaluation
          Turkiye
          Descriptive Statistics
          Body Mass Index
          T-Tests
          Mann-Whitney U Test
          Bivariate Statistics
          Pearson's Correlation Coefficient
          Step-Wise Multiple Regression
          Adult
          Middle Age
          Aged
          Male
          Female
          Multivariate Analysis
          Age Factors
          Sex Factors
          Convenience Sample
          Nonexperimental Studies
          Adult: 19-44 years
          Middle Aged: 45-64 years
          Aged: 65+ years
          Male
          Female
      ab: BACKGROUND: The aim of this study was to assess the association between cognitive function and age, pulmonary function, comorbidity index, and the 6-min walk distance in subjects with COPD as well as to compare the Mini Mental State Examination (MMSE) and Montreal Cognitive Assessment (MoCA) in terms of their ability to identify cognitive dysfunction in subjects with COPD. METHODS: A total of 52 individuals with stable COPD were included in this study. Cognitive function was assessed using MMSE and MoCA. Age, body mass index, the Modified Cumulative Illness Rating Scale, 6-min walk distance, arterial blood gases, and pulmonary function tests were assessed and recorded. RESULTS: The range and SD of scores in subjects with COPD were larger with MoCA than with MMSE. MMSE and MoCA scores are associated with 6-min walk distance and comorbidity index in subjects with COPD. General cognitive function measured by MoCA was negatively correlated with the comorbidity index but was positively associated with 6-min walk distance in subjects with COPD after controlling for possible confounding factors in the multivariate model. However, general cognitive function measured by MMSE was not correlated with the comorbidity index and 6-min walk distance in subjects with COPD, after controlling for possible confounding factors in the multivariate model. CONCLUSIONS: MoCA may be a more reliable screening test than MMSE in detecting cognitive impairment in subjects with COPD. The addition of cognitive tests on assessment of subjects with COPD can provide further benefit.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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