Stability of liver proton density fat fraction and changes in R * measurements induced by administering gadoxetic acid at 3T MRI.
Objective: To assess changes in liver proton density fat fraction (PDFF) and R * measurements in the presence of changes in tissue relaxation rates induced by administrating gadoxetic acid, using two different image reconstruction methods at 3T MRI. Methods: Forty-five patients were imaged at 3T wit...
| Publicado en: | Abdominal Radiology Vol. 41; no. 8; pp. 1555 - 1565 |
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| Autores principales: | , , , , |
| Formato: | Journal Article |
| Publicado: |
Springer Nature
Aug2016
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=117170704&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 117170704 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 2366004X JT14 jtl: Abdominal Radiology issn: 2366004X maglogo: N pubinfo: dt: Aug2016 vid: 41 iid: 8 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 117170704 10.1007/s00261-016-0728-5 117170704 ppf: 1555 ppct: 10 formats: fmt: @attributes: type: P tig: atl: Stability of liver proton density fat fraction and changes in R * measurements induced by administering gadoxetic acid at 3T MRI. aug: au: Sofue, Keitaro Zhong, Xiaodong Nickel, Marcel Dale, Brian Bashir, Mustafa affil: Siemens Healthcare , Atlanta USA sug: ab: Objective: To assess changes in liver proton density fat fraction (PDFF) and R * measurements in the presence of changes in tissue relaxation rates induced by administrating gadoxetic acid, using two different image reconstruction methods at 3T MRI. Methods: Forty-five patients were imaged at 3T with chemical-shift-based MRI sequences before and 20 min after administration of gadoxetic acid. Image reconstructions were performed using hybrid and complex methods to obtain PDFF and R * images. A single radiologist measured PDFF and R * values on precontrast and postcontrast images. Precontrast and postcontrast PDFF values were compared using intraclass correlation coefficient (ICC), linear regression, and Bland-Altman analysis. Changes in R * values from precontrast to postcontrast were correlated with relative liver enhancement (RLE) based on signal intensities on T -weighted images using Spearman's rank correlation. Results: PDFF values were similar between precontrast and postcontrast images (ICC = 0.99, linear regression slopes = 0.98, mean difference = −0.21 to −0.31%). PDFF measurements were stable between precontrast and postcontrast images. Changes in R * values were correlated with RLE ( p < 0.001, r = 0.49-0.71). Conclusions: PDFF measurements from both image reconstruction methods are stable in the presence of changes in tissue relaxation rates after administering gadoxetic acid at 3T MRI. Changes in R * values correlate with established measures of gadoxetic acid uptake based on T -weighted images. pubtype: Academic Journal doctype: Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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