Quantitative evaluation of beam-hardening artefact correction in dual-energy CT myocardial perfusion imaging.
Objectives: To assess quantitatively the impact of a novel reconstruction algorithm ("kernel") with beam-hardening correction (BHC) on beam-hardening artefacts of the myocardium at dual-energy CT myocardial perfusion imaging (DE-CTMPI).Methods: Rest-series of DE-CTMPI examinations from 14 patients w...
| Publicado en: | European Radiology Vol. 26; no. 9; pp. 3215 - 3223 |
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| Autores principales: | , , , , , , , , , , , , , , , , , , , |
| Formato: | diagnostic images research tables/charts Journal Article |
| Publicado: |
Springer Nature
Sep2016
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=117171326&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 117171326 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 09387994 NPH jtl: European Radiology issn: 09387994 maglogo: N pubinfo: dt: Sep2016 vid: 26 iid: 9 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 117171326 117171326 NLM26650935 117171326 10.1007/s00330-015-4137-x NLM26650935 117171326 ppf: 3215 ppct: 8 formats: fmt: @attributes: type: P tig: atl: Quantitative evaluation of beam-hardening artefact correction in dual-energy CT myocardial perfusion imaging. aug: au: Bucher, Andreas Wichmann, Julian Schoepf, U. Wolla, Christopher Canstein, Christian McQuiston, Andrew Krazinski, Aleksander De Cecco, Carlo Meinel, Felix Vogl, Thomas Geyer, Lucas Bucher, Andreas M Wichmann, Julian L Schoepf, U Joseph Wolla, Christopher D McQuiston, Andrew D Krazinski, Aleksander W De Cecco, Carlo N Meinel, Felix G Vogl, Thomas J affil: Division of Cardiovascular Imaging, Department of Radiology and Radiological Science , Medical University of South Carolina , Ashley River Tower, MSC 226, 25 Courtenay Drive Charleston 29401 USA sug: subj: Tomography, X-Ray Computed Methods Radiographic Image Interpretation, Computer-Assisted Methods Heart Retrospective Design Female Middle Age Algorithms Aged Male Sensitivity and Specificity Tomography, Emission-Computed, Single-Photon Reproducibility of Results Artifacts Human Middle Aged: 45-64 years Aged: 65+ years Female Male ab: Objectives: To assess quantitatively the impact of a novel reconstruction algorithm ("kernel") with beam-hardening correction (BHC) on beam-hardening artefacts of the myocardium at dual-energy CT myocardial perfusion imaging (DE-CTMPI).Methods: Rest-series of DE-CTMPI examinations from 14 patients were retrospectively analyzed. Six image series were reconstructed for each patient: a) 100 kV, b) 140 kV, and c) linearly blended MIX0.5, each with BHC (D33f kernel) and without (D30f kernel). Seven hundred and fifty-six myocardial regions were assessed. Seven equal regions of interest divided the myocardium in the axial section. Three subdivisions were created within these regions in areas prone to BHA. Reports of SPECT studies performed within 30 days of CT examination were used to confirm the presence and location of true perfusion defects. Paired student t-test was used for statistical evaluation.Results: Overall mean myocardial attenuation was lower using BHC (D30f: 87.3 ± 24.1 HU; D33f: 85.5 ± 21.5 HU; p = 0.009). Overall relative difference from average myocardial attenuation (RDMA) was more homogeneous using BHC (D30f: -0.3 ± 11.4 %; D33f: 0.1 ± 10.1 %; p < 0.001). Changes in RDMA were greatest in the posterobasal myocardium (D30f: -16.2 ± 10.0 %; D33f: 3.4 ± 10.7 %; p < 0.001).Conclusions: A dedicated reconstruction algorithm with BHC can significantly reduce beam-hardening artefacts in DE-CTMPI.Key Points: • Beam-hardening artefacts (BHA) cause interference with attenuation-based CT myocardial perfusion assessment (CTMPI). • BHA occur mostly in the posterobasal left ventricular wall. • Beam-hardening correction homogenized and decreased mean myocardial attenuation. • BHC can help avoid false-positive findings and increase specificity of static CTMPI. pubtype: Academic Journal doctype: diagnostic images research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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