Diagnostic accuracy of low-mA chest CT reconstructed with Model Based Iterative Reconstruction in the detection of early pleuro-pulmonary complications following a lung transplantation.

Objectives: To assess the accuracy of reduced-dose, low-mA chest CT (RD-CT) reconstructed with model-based iterative reconstruction (MBIR) in detecting usual early complications following pulmonary transplantation, as compared to standard-dose chest CT (SD-CT) reconstructed with adaptative statistic...

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Publicado en:European Radiology Vol. 26; no. 9; pp. 3138 - 3147
Autores principales: Debray, Marie-Pierre, Dauriat, Gaëlle, Khalil, Antoine, Leygnac, Sebastien, Tubiana, Sarah, Grandjean, Albane, Schouman-Claeys, Elisabeth, Laissy, Jean-Pierre, Ou, Phalla
Formato: diagnostic images research tables/charts Journal Article
Publicado: Springer Nature Sep2016
Acceso en línea:Ver este registro en EBSCOhost
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      pub: Springer Nature
      place: New York, New York
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        atl: Diagnostic accuracy of low-mA chest CT reconstructed with Model Based Iterative Reconstruction in the detection of early pleuro-pulmonary complications following a lung transplantation.
      aug:
        au:
          Debray, Marie-Pierre
          Dauriat, Gaëlle
          Khalil, Antoine
          Leygnac, Sebastien
          Tubiana, Sarah
          Grandjean, Albane
          Schouman-Claeys, Elisabeth
          Laissy, Jean-Pierre
          Ou, Phalla
        affil: Department of Radiology , AP-HP, Bichat-Claude Bernard Hospital , Paris France
      sug:
        subj:
          Pleura
          Tomography, X-Ray Computed Methods
          Lung Diseases Diagnosis
          Lung
          Radiography, Thoracic Methods
          Pleural Diseases Diagnosis
          Lung Transplantation Adverse Effects
          Algorithms
          Models, Theoretical
          Male
          Radiation Dosage
          Female
          Middle Age
          Prospective Studies
          Adult
          Human
          Middle Aged: 45-64 years
          Adult: 19-44 years
          Male
          Female
      ab: Objectives: To assess the accuracy of reduced-dose, low-mA chest CT (RD-CT) reconstructed with model-based iterative reconstruction (MBIR) in detecting usual early complications following pulmonary transplantation, as compared to standard-dose chest CT (SD-CT) reconstructed with adaptative statistical iterative reconstruction (ASIR).Methods: Our institutional review board approved this prospective study and patients provided written informed consent. Two thoracic radiologists independently evaluated 47 examinations performed routinely in 20 patients during 6 months following lung transplantation for the detection and/or evolution of usual pleuropulmonary complications and for subjective image quality. Each examination consisted of successive acquisition of unenhanced SD-CT (100-120 kV, noise index 45, ASIR) and RD-CT (100 kV, 16-24mAs/slice, MBIR).Results: Mean CTDIvol was 4.12 ± 0.88 and 0.65 ± 0.09 mGy for SD-CT and RD-CT, respectively. Complications were found in 40/47 (85 %) examinations. Sensitivity and negative predictive value of RD-CT were 92-100 % for the detection of pneumonia, fungal infection, pleural effusion, pneumothorax, and bronchial dehiscence or stenosis, as compared to SD-CT. Image quality of RD-CT was graded good for 81 % of examinations.Conclusions: MBIR-RD-CT is accurate, as compared to SD-CT, for delineating most usual pleuropulmonary complications during the 6 months following pulmonary transplantation and might be used routinely for the early monitoring of pulmonary allografts.Key Points: • Early chest complications are frequent following a pulmonary transplantation • CT has a key role for their detection and follow-up • Low-mAMBIR CT is accurate for monitoring most lung allograft early pleuropulmonary complications • MBIR chest CT allows a six-fold dose reduction compared to standard CT.
      pubtype: Academic Journal
      doctype:
        diagnostic images
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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