Volumetric Magnetic Resonance Imaging Study of Brain and Cerebellum in Children with Cerebral Palsy.
Introduction. Quantitative magnetic resonance imaging (MRI) studies are rarely used in the diagnosis of patients with cerebral palsy. The aim of present study was to assess the relationships between the volumetric MRI and clinical findings in children with cerebral palsy compared to control subjects...
| Publicado en: | BioMed Research International Vol. 2016; pp. 1 - 10 |
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| Autores principales: | , , |
| Formato: | diagnostic images research tables/charts Journal Article |
| Publicado: |
Wiley-Blackwell
8/4/2016
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=117191152&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 117191152 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 23146133 FT2T jtl: BioMed Research International issn: 23146133 maglogo: N pubinfo: dt: 8/4/2016 vid: 2016 pid: 480 pub: Wiley-Blackwell place: Malden, Massachusetts artinfo: ui: 117191152 117191152 117191152 10.1155/2016/5961928 117191152 ppf: 1 ppct: 9 formats: fmt: @attributes: type: P tig: atl: Volumetric Magnetic Resonance Imaging Study of Brain and Cerebellum in Children with Cerebral Palsy. aug: au: Kułak, Piotr Maciorkowska, Elżbieta Gościk, Elżbieta affil: Department of Pediatric Radiology, Medical University of Białystok, 15-274 Białystok, Poland sug: subj: Cerebral Palsy Pathology Magnetic Resonance Imaging Methods Brain Analysis Cerebellum Analysis Human Male Female Descriptive Statistics Body Weights and Measures Comparative Studies Poland Cerebral Ventricles Language Development Motor Skills Disorders Intellectual Disability Retrospective Design Scales Data Analysis Software Chi Square Test Wilcoxon Signed Rank Test T-Tests Linear Regression Apgar Score P-Value Child Adolescence Infant Child, Preschool Child: 6-12 years Adolescent: 13-18 years Infant: 1-23 months Child, Preschool: 2-5 years Male Female ab: Introduction. Quantitative magnetic resonance imaging (MRI) studies are rarely used in the diagnosis of patients with cerebral palsy. The aim of present study was to assess the relationships between the volumetric MRI and clinical findings in children with cerebral palsy compared to control subjects. Materials and Methods. Eighty-two children with cerebral palsy and 90 age- and sex-matched healthy controls were collected. Results. The dominant changes identified on MRI scans in children with cerebral palsy were periventricular leukomalacia (42%) and posthemorrhagic hydrocephalus (21%). The total brain and cerebellum volumes in children with cerebral palsy were significantly reduced in comparison to controls. Significant grey matter volume reduction was found in the total brain in children with cerebral palsy compared with the control subjects. Positive correlations between the age of the children of both groups and the grey matter volumes in the total brain were found. Negative relationship between width of third ventricle and speech development was found in the patients. Positive correlations were noted between the ventricles enlargement and motor dysfunction and mental retardation in children with cerebral palsy. Conclusions. By using the voxel-based morphometry, the total brain, cerebellum, and grey matter volumes were significantly reduced in children with cerebral palsy. pubtype: Academic Journal doctype: diagnostic images research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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