Acceptability and feasibility of point-of-care CD4 testing on HIV continuum of care in low and middle income countries: a systematic review.
Background: CD4 testing is, and will remain an important part of HIV treatment and care in low and middle income countries (LMICs). We report the findings of a systematic review assessing acceptability and feasibility of POC CD4 testing in field settings.Methods: Electronic databases were searched f...
| Published in: | BMC Health Services Research Vol. 16; pp. 1 - 13 |
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| Main Authors: | , , , , , , |
| Format: | research systematic review tables/charts Journal Article |
| Published: |
BioMed Central
8/2/2016
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| Online Access: | View this record in EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=117310937&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 117310937 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 14726963 1CHS jtl: BMC Health Services Research issn: 14726963 maglogo: N pubinfo: dt: 8/2/2016 vid: 16 pid: 24147 pub: BioMed Central artinfo: ui: 117310937 117310937 NLM27484023 117310937 10.1186/s12913-016-1588-y NLM27484023 PMC4971709 117310937 ppf: 1 ppct: 12 formats: tig: atl: Acceptability and feasibility of point-of-care CD4 testing on HIV continuum of care in low and middle income countries: a systematic review. aug: au: Pham, Minh D. Agius, Paul A. Romero, Lorena McGlynn, Peter Anderson, David Crowe, Suzanne M. Luchters, Stanley affil: Burnet Institute, Melbourne, VIC, Australia sug: subj: Anti-HIV Agents Continuity of Patient Care CD4 Lymphocyte Count Personal Satisfaction Primary Health Care Adult Male Equipment Failure Female Blood Specimen Collection Developing Countries Middle Age Systematic Review Human Adult: 19-44 years Middle Aged: 45-64 years Male Female ab: Background: CD4 testing is, and will remain an important part of HIV treatment and care in low and middle income countries (LMICs). We report the findings of a systematic review assessing acceptability and feasibility of POC CD4 testing in field settings.Methods: Electronic databases were searched for studies published in English between 2005 and 2015 that describe POC CD4 platforms. Studies conducted in LMICs and under field conditions outside a laboratory environment were eligible. Qualitative and descriptive data analysis was used to present the findings.Results: Twelve studies were included, 11 of which were conducted in sub-Saharan countries and used one POC CD4 test (The Alere Pima CD4). Patients reported positively regarding the implementation of POC CD4 testing at primary health care and community level with ≥90 % of patients accepting the test across various study settings. Health service providers expressed preference toward POC CD4 testing as it is easy-to-use, efficient and satisfied patients' needs to a greater extent as compared to conventional methods. However, operational challenges including preference toward venous blood rather than finger-prick sampling, frequent device failures and operator errors, quality of training for test operators and supervisors, and increased staff workload were also identified.Conclusions: POC CD4 testing seems acceptable and feasible in LIMCs under field conditions. Further studies using different POC CD4 tests available on the market are required to provide critical data to support countries in selection and implementation of appropriate POC CD4 technologies. pubtype: Academic Journal doctype: research systematic review tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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