Endoplasmic reticulum stress, unfolded protein response and development of colon adenocarcinoma.
When misfolded proteins accumulate in the endoplasmic reticulum (ER), the cell is said to experience ER stress. This triggers an unfolded protein response (UPR) to restore the balance between misfolded proteins and ER chaperones such as BiP. UPR signalling is required for the growth of many solid ca...
| Publicado en: | Virchows Archiv: European Journal of Pathology Vol. 469; no. 2; pp. 145 - 155 |
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| Autores principales: | , , , , , , , |
| Formato: | Journal Article |
| Publicado: |
Springer Nature
Aug2016
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| Acceso en línea: | Ver este registro en EBSCOhost |