Enhanced gray-white matter differentiation on non-enhanced CT using a frequency selective non-linear blending.

Introduction: The aim if this study is to find out if contrast between gray (GM) and white matter (WM) on non-enhanced brain CT (NECT) can be enhanced by using a frequency selective non-linear blending. Methods: Thirty consecutive patients (40 % female; mean age 67.73 ± 12.71 years), who underwent N...

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Published in:Neuroradiology Vol. 58; no. 7; pp. 649 - 656
Main Authors: Bier, Georg, Bongers, Malte, Ditt, Hendrik, Bender, Benjamin, Ernemann, Ulrike, Horger, Marius
Format: diagnostic images equations & formulas research tables/charts Journal Article
Published: Springer Nature Jul2016
Online Access:View this record in EBSCOhost
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      dt: Jul2016
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      pub: Springer Nature
      place: New York, New York
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        10.1007/s00234-016-1674-1
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        atl: Enhanced gray-white matter differentiation on non-enhanced CT using a frequency selective non-linear blending.
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          Bier, Georg
          Bongers, Malte
          Ditt, Hendrik
          Bender, Benjamin
          Ernemann, Ulrike
          Horger, Marius
        affil: Department of Diagnostic and Interventional Radiology , Eberhard Karls-University Tuebingen , Hoppe-Seyler-Str. 3 72076 Tuebingen Germany
      sug:
        subj:
          Brain Radiography
          Tomography, X-Ray Computed Methods
          Radiographic Image Enhancement Methods
          Gray Matter Radiography
          Human
          Contrast Media
          Neuroradiography
          Female
          Male
          Middle Age
          Aged
          Aged, 80 and Over
          Retrospective Design
          Algorithms
          Image Interpretation, Computer Assisted
          Descriptive Statistics
          P-Value
          Multidetector Computed Tomography
          Image Processing, Computer Assisted
          Middle Aged: 45-64 years
          Aged: 65+ years
          Aged, 80 & over
          Female
          Male
      ab: Introduction: The aim if this study is to find out if contrast between gray (GM) and white matter (WM) on non-enhanced brain CT (NECT) can be enhanced by using a frequency selective non-linear blending. Methods: Thirty consecutive patients (40 % female; mean age 67.73 ± 12.71 years), who underwent NECT of the brain, were retrospectively included in this study. Brain scan readings were performed by two radiologists independently, for NECT and subsequently the images were read using a new frequency selective non-linear blending algorithm (best contrast, BC). Optimal settings of BC for enhanced delineation of anatomical structures were set at an averaged center of 30 HU, averaged delta of 5 HU, and a slope of 5. For contrast-to-noise ratio calculation (CNR), gray and white matter attenuation values were measured for both NECT and BC in different anatomical structures. Results: CNR increase in the gray matter was 5.91 ± 2.45 for the cortical gray matter and 4.41 ± 1.82 for the basal ganglia. The contrast ratio between cortical gray and white matter was 1.87 and 1.7 (basal ganglia/WM) for BC quantification vs. 1.43 (cortex/WM) and 1.33 (basal ganglia/WM) for standard NECT (both p < 0.0001). Improved CNR did not depend on the anatomical structures measured. Conclusion: Frequency selective non-linear blending allows better discrimination between WM and GM and therefore may enhance diagnostic accuracy of NECT.
      pubtype: Academic Journal
      doctype:
        diagnostic images
        equations & formulas
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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