A review of metaphase chromosome image selection techniques for automatic karyotype generation.
The karyotype is analyzed to detect the genetic abnormalities. It is generated by arranging the chromosomes after extracting them from the metaphase chromosome images. The chromosomes are non-rigid bodies that contain the genetic information of an individual. The metaphase chromosome image spread co...
| Publicado en: | Medical & Biological Engineering & Computing Vol. 54; no. 8; pp. 1147 - 1158 |
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| Autores principales: | , |
| Formato: | review Journal Article |
| Publicado: |
Springer Nature
Aug2016
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=117360500&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 117360500 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 01400118 PO0 jtl: Medical & Biological Engineering & Computing issn: 01400118 maglogo: N pubinfo: dt: Aug2016 vid: 54 iid: 8 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 117360500 117360500 NLM26676686 117360500 10.1007/s11517-015-1419-z NLM26676686 117360500 ppf: 1147 ppct: 11 formats: fmt: @attributes: type: P tig: atl: A review of metaphase chromosome image selection techniques for automatic karyotype generation. aug: au: Arora, Tanvi Dhir, Renu affil: Department of Computer Science and Engineering , Dr. B.R. Ambedkar National Institute of Technology , Jalandhar India sug: subj: Image Processing, Computer Assisted Methods Karyotyping Cell Physiology ab: The karyotype is analyzed to detect the genetic abnormalities. It is generated by arranging the chromosomes after extracting them from the metaphase chromosome images. The chromosomes are non-rigid bodies that contain the genetic information of an individual. The metaphase chromosome image spread contains the chromosomes, but these chromosomes are not distinct bodies; they can either be individual chromosomes or be touching one another; they may be bent or even may be overlapping and thus forming a cluster of chromosomes. The extraction of chromosomes from these touching and overlapping chromosomes is a very tedious process. The segmentation of a random metaphase chromosome image may not give us correct and accurate results. Therefore, before taking up a metaphase chromosome image for analysis, it must be analyzed for the orientation of the chromosomes it contains. The various reported methods for metaphase chromosome image selection for automatic karyotype generation are compared in this paper. After analysis, it has been concluded that each metaphase chromosome image selection method has its advantages and disadvantages. pubtype: Academic Journal doctype: review Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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