Pyostomatitis vegetans (PSV)-pyodermatitis vegetans (PDV): A clinicopathologic study of 7 cases at a tertiary referral center.
Background: Pyostomatitis vegetans (PSV)-pyodermatitis vegetans (PDV) is a rare inflammatory mucocutaneous disease associated with inflammatory bowel disease.Objective: We sought to evaluate the clinicopathologic findings of PSV-PDV in a series of 7 patients.Methods: We conducted a retrospective rev...
| Publicado en: | Journal of the American Academy of Dermatology Vol. 75; no. 3; pp. 578 - 585 |
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| Autores principales: | , , , |
| Formato: | case study research Journal Article |
| Publicado: |
Elsevier B.V.
Sep2016
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=117495991&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 117495991 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 01909622 1ZF jtl: Journal of the American Academy of Dermatology issn: 01909622 maglogo: N pubinfo: dt: Sep2016 vid: 75 iid: 3 pid: 467 pub: Elsevier B.V. place: New York, New York artinfo: ui: 117495991 117495991 NLM27349819 117495991 10.1016/j.jaad.2016.03.047 NLM27349819 117495991 ppf: 578 ppct: 7 formats: tig: atl: Pyostomatitis vegetans (PSV)-pyodermatitis vegetans (PDV): A clinicopathologic study of 7 cases at a tertiary referral center. aug: au: Clark, Leon G. Tolkachjov, Stanislav N. Bridges, Alina G. Camilleri, Michael J. affil: Mayo Medical School, College of Medicine, Mayo Clinic, Rochester, Minnesota sug: subj: Pyoderma Pathology Pyoderma Epidemiology Stomatitis Epidemiology Stomatitis Pathology Inflammatory Bowel Diseases Epidemiology Inflammatory Bowel Diseases Diagnosis Incidence Demography Probability Sample Biopsy, Needle Comorbidity Male Immunohistochemistry Hospitals, Special Adult Stomatitis Diagnosis Pyoderma Diagnosis Young Adult Severity of Illness Indices Female Middle Age Retrospective Design Risk Assessment Prognosis Human Adult: 19-44 years Middle Aged: 45-64 years Male Female ab: Background: Pyostomatitis vegetans (PSV)-pyodermatitis vegetans (PDV) is a rare inflammatory mucocutaneous disease associated with inflammatory bowel disease.Objective: We sought to evaluate the clinicopathologic findings of PSV-PDV in a series of 7 patients.Methods: We conducted a retrospective review of all cases of PSV-PDV at the Mayo Clinic from 1995 to 2014.Results: Seven patients with PSV-PDV were included, and all had inflammatory bowel disease. Three had Crohn's disease and 4 had ulcerative colitis. Three patients had peripheral blood eosinophilia. Two had concomitant pyoderma gangrenosum in which pyoderma gangrenosum lesions were recalcitrant to therapy. Primary sclerosing cholangitis was seen in 3 patients. Two patients had direct and 3 had indirect immunofluorescence findings. Tissue eosinophilia was seen in the majority of mucosal and cutaneous lesions.Limitations: Limited sample size and retrospective study design are limitations.Conclusions: PSV-PDV is associated with inflammatory bowel disease and primary sclerosing cholangitis and may precede gastrointestinal symptoms. Immunofluorescence findings in select PSV-PDV cases may indicate possible overlap with autoimmune bullous disease. Tissue eosinophilia may be helpful in distinguishing PSV-PDV from pyoderma gangrenosum. Strict control of bowel disease and close monitoring of patients with subclinical disease is warranted. pubtype: Academic Journal doctype: case study research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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