Prevalence, Duration, Severity, and Distress of Chemotherapy-Related Gastrointestinal Symptoms in Patients With a Hematologic Malignancy.

Purpose/Objectives: To describe prevalence, duration, severity, and distress of chemotherapy-related gastrointestinal (GI) symptoms, and evaluate inclusion of clinically relevant GI symptom items on cancer symptom questionnaires. Design: Longitudinal descriptive design. Setting: Inpatient and outpat...

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Publicado en:Oncology Nursing Forum Vol. 43; no. 5; pp. 561 - 572
Autor principal: Cherwin, Catherine
Formato: research tables/charts Journal Article
Publicado: Oncology Nursing Society Sep2016
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Sep2016
      vid: 43
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      pub: Oncology Nursing Society
      place: Pittsburgh, Pennsylvania
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        atl: Prevalence, Duration, Severity, and Distress of Chemotherapy-Related Gastrointestinal Symptoms in Patients With a Hematologic Malignancy.
      aug:
        au: Cherwin, Catherine
        affil: Professor, School of Nursing, University of Wisconsin, Madison
      sug:
        subj:
          Hematologic Neoplasms Drug Therapy
          Chemotherapy, Adjuvant Adverse Effects
          Stress, Psychological
          Gastrointestinal Diseases Epidemiology
          Gastrointestinal Diseases Chemically Induced
          Human
          Prospective Studies
          Descriptive Research
          Prevalence
          Severity of Illness
          Gastrointestinal Diseases Symptoms
          Descriptive Statistics
          Questionnaires
          Comparative Studies
          Convenience Sample
          Self Report
          Comorbidity
          Scales
          Middle Age
          Male
          Female
          Funding Source
          Middle Aged: 45-64 years
          Male
          Female
      ab: Purpose/Objectives: To describe prevalence, duration, severity, and distress of chemotherapy-related gastrointestinal (GI) symptoms, and evaluate inclusion of clinically relevant GI symptom items on cancer symptom questionnaires. Design: Longitudinal descriptive design. Setting: Inpatient and outpatient hematology settings. Sample: 105 adults with a hematologic malignancy receiving their third or subsequent cycle of chemotherapy. Methods: Participants completed weekly assessments of 19 GI symptoms during a three-week period of chemotherapy. Descriptive statistics were calculated to summarize GI symptom prevalence, duration, severity, and distress ratings at each week. Findings were compared to item content of 12 cancer multisymptom questionnaires identified in the literature. Main Research Variables: GI symptom prevalence, duration, severity, and distress. Findings: Participants reported an average of three to five GI symptoms at each time point that were typically experienced as mild to moderate in duration, severity, and distress. Only 3 of 11 clinically relevant GI symptoms were included on more than half of the cancer symptom questionnaires. Conclusions: Patients receiving chemotherapy experience a moderate GI symptom burden across a wide range of potential GI symptoms. Implications for Nursing: Future research should include measures of clinically relevant GI symptoms that may be emerging with new cancer therapies and toxicity prevention protocols.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
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      ougenre: Article
    language: English
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