FABS: An Intuitive Tool for Screening of Stroke Mimics in the Emergency Department.

Background and Purpose: A large number of patients with symptoms of acute cerebral ischemia are stroke mimics (SMs). In this study, we sought to develop a scoring system (FABS) for screening and stratifying SM from acute cerebral ischemia and to identify patients who may require magnetic resonance i...

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Publicado en:Stroke (00392499) Vol. 47; no. 9; pp. 2216 - 2221
Autores principales: Goyal, Nitin, Tsivgoulis, Georgios, Male, Shailesh, Metter, E. Jeffrey, Iftikhar, Sulaiman, Kerro, Ali, Chang, Jason J., Frey, James L., Triantafyllou, Sokratis, Papadimitropoulos, Georgios, Abedi, Vida, Alexandrov, Anne W., Alexandrov, Andrei V., Zand, Ramin
Formato: Journal Article
Publicado: Lippincott Williams & Wilkins Sep2016
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Sep2016
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      pub: Lippincott Williams & Wilkins
      place: Baltimore, Maryland
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        117674688
        117674688
        NLM27491733
        10.1161/STROKEAHA.116.013842
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        117674688
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        atl: FABS: An Intuitive Tool for Screening of Stroke Mimics in the Emergency Department.
      aug:
        au:
          Goyal, Nitin
          Tsivgoulis, Georgios
          Male, Shailesh
          Metter, E. Jeffrey
          Iftikhar, Sulaiman
          Kerro, Ali
          Chang, Jason J.
          Frey, James L.
          Triantafyllou, Sokratis
          Papadimitropoulos, Georgios
          Abedi, Vida
          Alexandrov, Anne W.
          Alexandrov, Andrei V.
          Zand, Ramin
        affil: Department of Neurology, University of Tennessee Health Science Center, Memphis
      sug:
        subj:
          Stroke Diagnosis
          Cerebral Ischemia Diagnosis
          Sensitivity and Specificity
          Emergency Medical Services
          Diagnosis, Differential
          Male
          Middle Age
          Magnetic Resonance Imaging
          Stroke
          Emergency Service
          Adult
          Aged
          Cerebral Ischemia
          Female
          Middle Aged: 45-64 years
          Adult: 19-44 years
          Aged: 65+ years
          Male
          Female
      ab: Background and Purpose: A large number of patients with symptoms of acute cerebral ischemia are stroke mimics (SMs). In this study, we sought to develop a scoring system (FABS) for screening and stratifying SM from acute cerebral ischemia and to identify patients who may require magnetic resonance imaging to confirm or refute a diagnosis of stroke in the emergency setting.Methods: We designed a scoring system: FABS (6 variables with 1 point for each variable present): absence of Facial droop, negative history of Atrial fibrillation, Age <50 years, systolic Blood pressure <150 mm Hg at presentation, history of Seizures, and isolated Sensory symptoms without weakness at presentation. We evaluated consecutive patients with symptoms of acute cerebral ischemia and a negative head computed tomography for any acute finding within 4.5 hours after symptom onset in 2 tertiary care stroke centers for validation of FABS.Results: A total of 784 patients (41% SMs) were evaluated. Receiver operating characteristic curve (C statistic, 0.95; 95% confidence interval [CI], 0.93-0.98) indicated that FABS≥3 could identify patients with SM with 90% sensitivity (95% CI, 86%-93%) and 91% specificity (95% CI, 88%-93%). The negative predictive value and positive predictive value were 93% (95% CI, 90%-95%) and 87% (95% CI, 83%-91%), respectively.Conclusions: FABS seems to be reliable in stratifying SM from acute cerebral ischemia cases among patients in whom the head computed tomography was negative for any acute findings. It can help clinicians consider advanced imaging for further diagnosis.
      pubtype: Academic Journal
      doctype: Journal Article
      ougenre: Article
    language: English
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