Adhesio interthalamica and cavum septum pellucidum in mesial temporal lobe epilepsy.
The absence of the adhesio interthalamica (AI; also called interthalamic adhesion or massa intermedia) and the presence of a large cavum septum pellucidum (CSP) later in life have been related to neurodevelopmental alterations and have not been systematically investigated in epilepsy to date. This s...
| Publicado en: | Brain Imaging & Behavior Vol. 10; no. 3; pp. 849 - 857 |
|---|---|
| Autores principales: | , , , , , , , , , , , , , , , , , , |
| Formato: | research Journal Article |
| Publicado: |
Springer Nature
Sep2016
|
| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=117723647&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 117723647 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 19317557 3GSC jtl: Brain Imaging & Behavior issn: 19317557 maglogo: N pubinfo: dt: Sep2016 vid: 10 iid: 3 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 117723647 117723647 NLM26497889 117723647 10.1007/s11682-015-9461-x NLM26497889 117723647 ppf: 849 ppct: 8 formats: fmt: @attributes: type: P tig: atl: Adhesio interthalamica and cavum septum pellucidum in mesial temporal lobe epilepsy. aug: au: Trzesniak, Clarissa Linares, Ila Coimbra, Érica Júnior, Alexandre Velasco, Tonicarlo Santos, Antonio Hallak, Jaime Sakamoto, Americo Busatto, Geraldo Crippa, José Linares, Ila M Coimbra, Érica R Júnior, Alexandre Veriano Velasco, Tonicarlo R Santos, Antonio C Hallak, Jaime E Sakamoto, Americo C Busatto, Geraldo F Crippa, José A affil: Department of Neurosciences and Behaviour, Medical School , University of São Paulo (USP) , Ribeirão Preto Brazil sug: subj: Epilepsy, Temporal Lobe Thalamus Male Sclerosis Sclerosis Psychosocial Factors Body Weights and Measures Adult Neuropsychological Tests Magnetic Resonance Imaging Epilepsy, Temporal Lobe Psychosocial Factors Female Human Adult: 19-44 years Male Female ab: The absence of the adhesio interthalamica (AI; also called interthalamic adhesion or massa intermedia) and the presence of a large cavum septum pellucidum (CSP) later in life have been related to neurodevelopmental alterations and have not been systematically investigated in epilepsy to date. This study carried out a MRI evaluation of the AI and CSP in a large sample with mesial temporal lobe epilepsy (MTLE). A total of 179 patients, classified according to the side of the epileptogenic focus, and 156 age- and sex-balanced healthy controls were assessed. Between-group comparisons of the prevalence and length of both AI and CSP were conducted. Neuropsychological assessments were also performed in 160 MTLE patients. The patients exhibited reduction in the AI prevalence (P < 0.05; FDR-uncorrected) and length (P < 0.05; FDR-corrected) when compared to controls. Patients without AI showed lower scores in a proportion of neuropsychological tests than patients with AI. No CSP differences were found between MTLE patients and controls. These results support that AI anomalies have clinical significance in MTLE, as well as indicate that neurodevelopmental alterations may be implicated in this disorder. pubtype: Academic Journal doctype: research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
|---|