Association between Pattern of Gastritis and Gastroesophageal Reflux Disease in Patients with Helicobacter Pylori Infection.
BACKGROUND Reflux disease is a common gastrointestinal problem. The association between reflux disease and gastritis pattern is controversial. AIM: To determine the association between reflux disease and gastritis pattern in patients with Helicobacter pylori (H. pylori) infection. METHODS 470 patien...
| Publicado en: | Middle East Journal of Digestive Diseases Vol. 8; no. 3; pp. 206 - 212 |
|---|---|
| Autores principales: | , , , , , , , , , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Iranian Association of Gastroenterology & Hepatology
Jul2016
|
| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=117794714&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 117794714 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 20085230 BG4K jtl: Middle East Journal of Digestive Diseases issn: 20085230 maglogo: N pubinfo: dt: Jul2016 vid: 8 iid: 3 pid: 70725 pub: Iranian Association of Gastroenterology & Hepatology artinfo: ui: 117794714 117794714 117794714 10.15171/mejdd.2016.33 117794714 ppf: 206 ppct: 6 formats: fmt: @attributes: type: P tig: atl: Association between Pattern of Gastritis and Gastroesophageal Reflux Disease in Patients with Helicobacter Pylori Infection. aug: au: Nobakht, Hossein Boghratian, Amirhossein Sohrabi, Masoudreza Panahian, Mohammad Rakhshani, Naser Nikkhah, Mehdi Ajdarkosh, Hossein Hemmasi, Gholamreza Khonsari, Mahmoodreza Gholami, Ali Rabiei, Neda Zamani, Farhad affil: GastroIntestinal and Liver Disease Research Centre (GILDRC), Firoozgar Hospital, Iran University of Medical Sciences, Tehran, Iran sug: subj: Gastritis Diagnosis Gastroesophageal Reflux Diagnosis Helicobacter Infections Diagnosis Human Dyspepsia Adult Endoscopy Biopsy, Needle Pyloric Antrum Aged Middle Age Male Female Stomach Diseases Regression Odds Ratio Confidence Intervals Adult: 19-44 years Aged: 65+ years Middle Aged: 45-64 years Male Female ab: BACKGROUND Reflux disease is a common gastrointestinal problem. The association between reflux disease and gastritis pattern is controversial. AIM: To determine the association between reflux disease and gastritis pattern in patients with Helicobacter pylori (H. pylori) infection. METHODS 470 patients with dyspepsia and reflux disease were enrolled in this study. The inclusion criteria were willing to participate in the study, age over 40 years, and having the criteria of ROME III for at least 3 months. Patients with history of H. pylori eradication therapy during the 3 months before the study, a history of gastric surgery, and gastric cancer were excluded. All of the participants underwent upper endoscopy and two biopsy samples were taken from antrum, body, and fundal areas. RESULTS H. pylori infection rate was 367 (78.1%) with mean age of 59.8 ±11.4 years. Of them 131 patients (35.7%) were male. Reflux disease was detected in 273 (74.4%) patients. 216 (58.9%) and 102 (27.8%) patients had non-erosive reflux disease (NERD) and gastroesophageal reflux disease (GERD), respectively. Corpus predominant and antral predominant gastritis were seen in 72 (19.6%) and 129 (35.2%) patients, respectively. Antral gastritis was significantly associated with GERD (p<0.01). In regression analysis, antral predominant gastritis had a significant association with GERD (OR=1.92; 95%CI: 1.22-3.12). The same result was observed in mild to moderate antral and greater curvature gastritis (OR= 1.26; 95%CI: 0.25-6.40 and OR= 3.0; 95%CI: 0.63-14.17, respectively). CONCLUSION According to these finding,we could suggest that the pattern of gastritis could be associated with reflux disease and GERD. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
|---|