Occurrence of hepatotoxicity with pazopanib and other anti-VEGF treatments for renal cell carcinoma: an observational study utilizing a distributed database network.

Purpose: To quantify the hepatic safety of pazopanib and comparator anti-vascular endothelial growth factor (VEGF) therapies in clinical practice among renal cell carcinoma (RCC) patients.Methods: A population-based cohort study of new anti-VEGF users was conducted in two US healthcare databases, De...

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Bibliographic Details
Published in:Cancer Chemotherapy & Pharmacology Vol. 78; no. 3; pp. 559 - 567
Main Authors: Shantakumar, Sumitra, Nordstrom, Beth, Djousse, Luc, Hall, Susan, Gagnon, David, Fraeman, Kathy, Herk-Sukel, Myrthe, Chagin, Karen, Nelson, Jeanenne, Nordstrom, Beth L, Hall, Susan A, Gagnon, David R, Fraeman, Kathy H, van Herk-Sukel, Myrthe
Format: research Journal Article
Published: Springer Nature Sep2016
Online Access:View this record in EBSCOhost