EMBalance - validation of a decision support system in the early diagnostic evaluation and management plan formulation of balance disorders in primary care: study protocol of a feasibility randomised controlled trial.

Background: Balance problems are caused by multiple factors and often lead to falls and related fractures, bringing large socio-economic costs. The complexity of balance control mechanisms, the lack of medical expertise, and the absence of specialised equipment contribute to the delayed or incorrect...

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Published in:Trials Vol. 17; pp. 1 - 10
Main Authors: Rammazzo, Laura, Kikidis, Dimitris, Anwer, Amal, Macdonald, Nora, Kyrodimos, Efthymios, Maurer, Christoph, Wuyts, Floris, Luxon, Linda, Bibas, Athanasios, Bamiou, Doris-Eva
Format: Journal Article
Published: BioMed Central 9/5/2016
Online Access:View this record in EBSCOhost
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      dt: 9/5/2016
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      pub: BioMed Central
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        atl: EMBalance - validation of a decision support system in the early diagnostic evaluation and management plan formulation of balance disorders in primary care: study protocol of a feasibility randomised controlled trial.
      aug:
        au:
          Rammazzo, Laura
          Kikidis, Dimitris
          Anwer, Amal
          Macdonald, Nora
          Kyrodimos, Efthymios
          Maurer, Christoph
          Wuyts, Floris
          Luxon, Linda
          Bibas, Athanasios
          Bamiou, Doris-Eva
        affil: Neuro-otology Department, National Hospital for Neurology and Neurosurgery, Queen Square, London WC1N 3BG, UK
      sug:
      ab: Background: Balance problems are caused by multiple factors and often lead to falls and related fractures, bringing large socio-economic costs. The complexity of balance control mechanisms, the lack of medical expertise, and the absence of specialised equipment contribute to the delayed or incorrect diagnosis and management ofthese patients. Advances in computer science have allowed the development of computer systems that support clinical diagnosis and treatment decisions based on individualised patient data. The aim of the EMBalance decision support system (DSS) is to support doctors facing this clinical challenge, to make a definitive diagnosis and implement an effective management plan. The EMBalance study will determine the accuracy of this supportive tool when used by non-specialist doctors. This study is funded by the European Union's Seventh Framework Programme.Methods/design: EMBalance is a proof-of-concept study designed as a non-commercial, international, multi-centre, single-blind, parallel-group randomised controlled trial to be carried out at four clinical sites in the United Kingdom, Germany, Greece and Belgium. The study is comprised of three stages: internal pilot, phase I (diagnosis) and stage II (management). For this purpose, 200 patients presenting with persistent dizziness (>3 months' duration) to primary care services will be randomised to either the intervention group (diagnostic assessment with the DSS) or a control group (diagnostic assessment without the DSS). Patients allocated to the intervention group will be assessed by a doctor with the support of the EMBalance DSS, while patients allocated to the control group will receive a visit as per standard practice. Ultimately, all patients' diagnoses and management plans will be certified by a consultant in neuro-otology.Discussion: EMBalance is the first trial to test the accuracy of a DSS in both the diagnosis of and the management plan for vestibular disorders across the healthcare systems of four different countries. The EMBalance study is the result of a combined effort of engineers and physicians to develop an accurate tool to support non-specialist doctors, with no risk for the patient. This trial will provide reliable information about the benefits of implementing DSSs in primary care while supporting the feasibility of testing the EMBalance algorithms in further research.Trial Registration: ClinicalTrials.gov NCT02704819 . Registered 29 February 2016.
      pubtype: Academic Journal
      doctype: Journal Article
      ougenre: Article
    language: English
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