CD8-positive Mycosis Fungoides Masquerading as Pyoderma Gangrenosum.
Mycosis fungoides (MF), a primary cutaneous T-cell lymphoma, accounts for <1% of non-Hodgkin lymphomas. The diagnosis of classic MF is based on a constellation of typical clinical presentation, histopathology, immunohistochemistry, and T-cell monoclonality detected by molecular studies. Rarely, atyp...
| Publicado en: | Indian Journal of Dermatology Vol. 61; no. 5; pp. 579 - 582 |
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| Autores principales: | , , , |
| Formato: | case study diagnostic images pictorial Journal Article |
| Publicado: |
Wolters Kluwer India Pvt Ltd
Sep/Oct2016
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| Acceso en línea: | Ver este registro en EBSCOhost |
| Sumario: | Mycosis fungoides (MF), a primary cutaneous T-cell lymphoma, accounts for <1% of non-Hodgkin lymphomas. The diagnosis of classic MF is based on a constellation of typical clinical presentation, histopathology, immunohistochemistry, and T-cell monoclonality detected by molecular studies. Rarely, atypical clinical presentation may occur. The typical immunohistochemical phenotype is, CD2 +ve, CD3 +ve, CD5 +ve, CD4 +ve, and CD8 - ve. Here, we report a rare case of CD8 +ve MF in a 43-year-male patient who was clinically diagnosed as pyoderma gangrenosum initially. The atypical presentation and rarity of such case have prompted this report. |
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