Aetiology, comorbidities and cofactors of chronic leg ulcers: retrospective evaluation of 1 000 patients from 10 specialised dermatological wound care centers in Germany.

Numerous comorbidities and cofactors have been known to influence wound healing processes. In this multicentre study, clinical data of 1 000 patients with chronic leg ulcers from ten specialised dermatological wound care centers were analysed. The patient cohort comprised 567 females and 433 males w...

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Published in:International Wound Journal Vol. 13; no. 5; pp. 821 - 829
Main Authors: Jockenhöfer, Finja, Gollnick, Harald, Herberger, Katharina, Isbary, Georg, Renner, Regina, Stücker, Markus, Valesky, Eva, Wollina, Uwe, Weichenthal, Michael, Karrer, Sigrid, Kuepper, Bernhard, Roesch, Alexander, Dissemond, Joachim
Format: research tables/charts Journal Article
Published: Wiley-Blackwell Oct2016
Online Access:View this record in EBSCOhost
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      dt: Oct2016
      vid: 13
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      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        atl: Aetiology, comorbidities and cofactors of chronic leg ulcers: retrospective evaluation of 1 000 patients from 10 specialised dermatological wound care centers in Germany.
      aug:
        au:
          Jockenhöfer, Finja
          Gollnick, Harald
          Herberger, Katharina
          Isbary, Georg
          Renner, Regina
          Stücker, Markus
          Valesky, Eva
          Wollina, Uwe
          Weichenthal, Michael
          Karrer, Sigrid
          Kuepper, Bernhard
          Roesch, Alexander
          Dissemond, Joachim
        affil: Department of Dermatology, Venereology and Allergology, University Hospital of Essen, Essen Germany
      sug:
        subj:
          Leg Ulcer
          Ankle Brachial Index
          Venous Ulcer
          Pyoderma Gangrenosum
          Wound Care
          Wounds, Chronic
          Germany
          Female
          Male
          Data Analysis, Statistical
          Child
          Aged
          Cross Sectional Studies
          Descriptive Statistics
          Prospective Studies
          Data Collection
          Questionnaires
          Probability
          Child: 6-12 years
          Aged: 65+ years
          Female
          Male
      ab: Numerous comorbidities and cofactors have been known to influence wound healing processes. In this multicentre study, clinical data of 1 000 patients with chronic leg ulcers from ten specialised dermatological wound care centers were analysed. The patient cohort comprised 567 females and 433 males with an average age of 69·9 years. The wounds persisted on average for 40·8 months and had a mean size of 43·7 cm2. Venous leg ulcers represented the most common entity accounting for 51·3% of all chronic wounds, followed by mixed-type ulcers in 12·9% and arterial ulcerations in 11·0% of the patients. Vasculitis was diagnosed in 4·5%, trauma in 3·2%, pyoderma gangrenosum in 2·8%, lymphoedema in 1·7%, neoplasia in 1·0% and delayed post-surgical wound healing in 0·6% of the included patients. In total, 70·5% of patients suffered from arterial hypertension, 45·2% were obese, 27·2% had non-insulin dependent diabetes, and 24·4% dyslipidaemia. Altogether 18·4% suffered from metabolic syndrome. Cofactors and comorbidities of patients with chronic leg ulcers have previously been studied but not in detail. Here, we were able to demonstrate the existence of several potentially relevant cofactors, comorbidities of their associations and geographical distributions, which should be routinely examined in patients with chronic leg ulcers and - if possible - treated.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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