Low vascularity predicts favourable outcomes in leiomyoma patients treated with uterine artery embolization.

Objectives: To investigate the clinical factors predicting outcomes of leiomyoma treated with uterine artery embolization (UAE).Methods: A total of 183 uterine leiomyoma patients undergoing UAE were retrospectively analyzed. Patient age, characteristics of vascular supply in magnetic resonance imagi...

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Publicado en:European Radiology Vol. 26; no. 10; pp. 3571 - 3580
Autores principales: Tang, Yixin, Chen, Chunlin, Duan, Hui, Ma, Ben, Liu, Ping
Formato: Journal Article
Publicado: Springer Nature Oct2016
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Oct2016
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      pub: Springer Nature
      place: New York, New York
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        10.1007/s00330-016-4223-8
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        atl: Low vascularity predicts favourable outcomes in leiomyoma patients treated with uterine artery embolization.
      aug:
        au:
          Tang, Yixin
          Chen, Chunlin
          Duan, Hui
          Ma, Ben
          Liu, Ping
        affil: Department of Obstetrics and Gynecology , Nan fang Hospital of the Southern Medical University , Guangzhou 510515 People's Republic of China
      sug:
        subj:
          Leiomyoma Blood Supply
          Neovascularization, Pathologic
          Uterine Artery Embolization Methods
          Leiomyoma Therapy
          Uterine Neoplasms Blood Supply
          Uterine Neoplasms Therapy
          Neoplasm Recurrence, Local
          Uterine Neoplasms
          Angiography, Digital Subtraction Methods
          Retrospective Design
          Treatment Outcomes
          Leiomyoma
          Leiomyoma Pathology
          Prognosis
          Middle Age
          Risk Factors
          Female
          Magnetic Resonance Angiography Methods
          Adult
          Uterine Neoplasms Pathology
          Scales
          Middle Aged: 45-64 years
          Adult: 19-44 years
          Female
      ab: Objectives: To investigate the clinical factors predicting outcomes of leiomyoma treated with uterine artery embolization (UAE).Methods: A total of 183 uterine leiomyoma patients undergoing UAE were retrospectively analyzed. Patient age, characteristics of vascular supply in magnetic resonance imaging (MRI)/digital subtraction angiography (DSA), number, size and location of leiomyoma were recorded. Leiomyoma regrowth, new leiomyoma appearance and recurrence of any previously reported symptoms were carefully monitored over a mean follow-up of 30 months (median 32 months, range 12-80). Potential recurrence risk factors were analyzed by univariate and multivariate cox regression analysis.Results: Twenty-three recurrences were recorded. The difference in the vascularity classification systems between MRI and DSA was not statistically significant (P = 0.059). High vascularity in MRI, high vascularity in DSA and multiple leiomyoma showed a significant risk of recurrence using univariate and multivariate analysis (P = 0.004, P < 0.001 and P = 0.023, respectively). The other factors were not significantly associated with leiomyoma recurrence (P > 0.05).Conclusion: Low vascularity and solitary leiomyoma indicated favourable outcomes in patients treated with UAE.Key Points: • Low vascularity and solitary mass predicted favourable outcomes in UAE-treated patients. • MRI might provide information on vascularity in leiomyoma before UAE. • Variations in vascular supply, age, size, location were not associated with recurrence.
      pubtype: Academic Journal
      doctype: Journal Article
      ougenre: Article
    language: English
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