Automated tube voltage selection for radiation dose and contrast medium reduction at coronary CT angiography using 3(rd) generation dual-source CT.

Objectives: To investigate the relationship between automated tube voltage selection (ATVS) and body mass index (BMI) and its effect on image quality and radiation dose of coronary CT angiography (CCTA).Methods: We evaluated 272 patients who underwent CCTA with 3(rd) generation dual-source CT (DSCT)...

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Published in:European Radiology Vol. 26; no. 10; pp. 3608 - 3617
Main Authors: Mangold, Stefanie, Wichmann, Julian, Schoepf, U., Poole, Zachary, Canstein, Christian, Varga-Szemes, Akos, Caruso, Damiano, Bamberg, Fabian, Nikolaou, Konstantin, Cecco, Carlo, Wichmann, Julian L, Schoepf, U Joseph, Poole, Zachary B, De Cecco, Carlo N
Format: research Journal Article
Published: Springer Nature Oct2016
Online Access:View this record in EBSCOhost
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      dt: Oct2016
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      pub: Springer Nature
      place: New York, New York
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        atl: Automated tube voltage selection for radiation dose and contrast medium reduction at coronary CT angiography using 3(rd) generation dual-source CT.
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          Mangold, Stefanie
          Wichmann, Julian
          Schoepf, U.
          Poole, Zachary
          Canstein, Christian
          Varga-Szemes, Akos
          Caruso, Damiano
          Bamberg, Fabian
          Nikolaou, Konstantin
          Cecco, Carlo
          Wichmann, Julian L
          Schoepf, U Joseph
          Poole, Zachary B
          De Cecco, Carlo N
        affil: Division of Cardiovascular Imaging, Department of Radiology and Radiological Science , Medical University of South Carolina , Charleston USA
      sug:
        subj:
          Coronary Angiography Methods
          Human
          Aged
          Female
          Retrospective Design
          Radiographic Image Interpretation, Computer-Assisted Methods
          Contrast Media Administration and Dosage
          Drug Administration Schedule
          Sensitivity and Specificity
          Male
          Electrocardiography Methods
          Body Mass Index
          Adult
          Middle Age
          Radiation Dosage
          Validation Studies
          Comparative Studies
          Evaluation Research
          Multicenter Studies
          Ferrans and Powers Quality of Life Index
          Aged: 65+ years
          Adult: 19-44 years
          Middle Aged: 45-64 years
          Female
          Male
      ab: Objectives: To investigate the relationship between automated tube voltage selection (ATVS) and body mass index (BMI) and its effect on image quality and radiation dose of coronary CT angiography (CCTA).Methods: We evaluated 272 patients who underwent CCTA with 3(rd) generation dual-source CT (DSCT). Prospectively ECG-triggered spiral acquisition was performed with automated tube current selection and advanced iterative reconstruction. Tube voltages were selected by ATVS (70-120 kV). BMI, effective dose (ED), and vascular attenuation in the coronary arteries were recorded. Signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) were calculated. Five-point scales were used for subjective image quality analysis.Results: Image quality was rated good to excellent in 98.9 % of examinations without significant differences for proximal and distal attenuation (all p ≥ .0516), whereas image noise was rated significantly higher at 70 kV compared to ≥100 kV (all p < .0266). However, no significant differences were observed in SNR or CNR at 70-120 kV (all p ≥ .0829). Mean ED at 70-120 kV was 1.5 ± 1.2 mSv, 2.4 ± 1.5 mSv, 3.6 ± 2.7 mSv, 5.9 ± 4.0 mSv, 7.9 ± 4.2 mSv, and 10.7 ± 4.1 mSv, respectively (all p ≤ .0414). Correlation analysis showed a moderate association between tube voltage and BMI (r = .639).Conclusion: ATVS allows individual tube voltage adaptation for CCTA performed with 3(rd) generation DSCT, resulting in significantly decreased radiation exposure while maintaining image quality.Key Points: • Automated tube voltage selection allows an individual tube voltage adaption in CCTA. • A tube voltage-based reduction of contrast medium volume is feasible. • Image quality was maintained while radiation exposure was significantly decreased. • A moderate association between tube voltage and body mass index was found.
      pubtype: Academic Journal
      doctype:
        research
        Journal Article
      ougenre: Article
    language: English
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