Quantification of early fatty infiltration of the rotator cuff muscles: comparison of multi-echo Dixon with single-voxel MR spectroscopy.
Objectives: To evaluate quantification of early fatty infiltration in supraspinatus muscles with magnetic resonance (MR) imaging using a T2*-corrected multi-echo 3D-gradient-echo Dixon-based sequence (multi-echo Dixon) and compare it to proton-MR-spectroscopy.Methods: Sixty subjects (mean age 46 yea...
| Publicado en: | European Radiology Vol. 26; no. 10; pp. 3719 - 3728 |
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| Autores principales: | , , , , , , |
| Formato: | research Journal Article |
| Publicado: |
Springer Nature
Oct2016
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=118060293&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 118060293 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 09387994 NPH jtl: European Radiology issn: 09387994 maglogo: N pubinfo: dt: Oct2016 vid: 26 iid: 10 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 118060293 118060293 NLM26679183 118060293 10.1007/s00330-015-4144-y NLM26679183 118060293 ppf: 3719 ppct: 9 formats: fmt: @attributes: type: P tig: atl: Quantification of early fatty infiltration of the rotator cuff muscles: comparison of multi-echo Dixon with single-voxel MR spectroscopy. aug: au: Agten, Christoph Rosskopf, Andrea Gerber, Christian Pfirrmann, Christian Agten, Christoph A Rosskopf, Andrea B Pfirrmann, Christian W A affil: Radiology, Balgrist University Hospital, Forchstrasse 340, CH-8008, Zurich, Switzerland sug: subj: Rotator Cuff Adipose Tissue Observer Bias Young Adult Female Male Rotator Cuff Pathology Reproducibility of Results Aged, 80 and Over Adult Aged Adolescence Human Magnetic Resonance Spectroscopy Methods Middle Age Magnetic Resonance Imaging Methods Adipose Tissue Pathology Validation Studies Comparative Studies Evaluation Research Multicenter Studies Ferrans and Powers Quality of Life Index Aged, 80 & over Adult: 19-44 years Aged: 65+ years Adolescent: 13-18 years Middle Aged: 45-64 years Female Male ab: Objectives: To evaluate quantification of early fatty infiltration in supraspinatus muscles with magnetic resonance (MR) imaging using a T2*-corrected multi-echo 3D-gradient-echo Dixon-based sequence (multi-echo Dixon) and compare it to proton-MR-spectroscopy.Methods: Sixty subjects (mean age 46 years, 41 men) with good supraspinatus muscle quality on 1.5 T MR imaging were included. Fat percentage (FP) in the supraspinatus muscle was quantified using a multi-echo Dixon compared to single-voxel MR spectroscopy as reference standard. In 18 subjects the multi-echo Dixon was repeated to assess test-retest reliability. Measurements based on multi-echo Dixon were performed by two independent readers by placing regions-of-interest (ROIs) in the supraspinatus muscle corresponding to the MR-spectroscopy voxel. Intraclass and concordance correlation coefficients (ICC/CCC) were used for statistical analysis.Results: Test-retest reliability was substantial for reader 1 (ICC = 0.757) and almost perfect for reader 2 (ICC = 0.873). Inter-reader reliability for multi-echo Dixon was almost perfect (ICC = 0.893, P < .0005). Mean FP in all 60 subjects with multi-echo Dixon was 3.5 ± 1.6 for reader 1, 3.7 ± 1.8 for reader 2, and 2.8 ± 1.4 with MR spectroscopy. Correlation between multi-echo Dixon and MR spectroscopy was moderate (CCC = 0.641).Conclusion: The multi-echo Dixon sequence is a reliable method and comparable to MR-spectroscopy for quantification of low levels of fatty infiltration in the supraspinatus muscle.Key Points: • Multi-echo Dixon for low fat quantification in muscles is reliable. • Multi-echo Dixon low fat quantification is comparable to single-voxel MR spectroscopy • Multi-echo Dixon detects substantial differences in fatty infiltration within Goutallier 0-1. pubtype: Academic Journal doctype: research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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