Quantitative Evaluation of Adult Subglottic Stenosis Using Intraoperative Long-range Optical Coherence Tomography.

Objectives: To determine the feasibility of long-range optical coherence tomography (LR-OCT) as a tool to intraoperatively image and measure the subglottis and trachea during suspension microlaryngoscopy before and after endoscopic treatment of subglottic stenosis (SGS). Methods: Long-range optical...

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Publicado en:Annals of Otology, Rhinology & Laryngology Vol. 125; no. 10; pp. 815 - 823
Autores principales: Sharma, Giriraj K., Chin Loy, Anthony, Su, Erica, Jing, Joe, Chen, Zhongping, Wong, Brian J-F., Verma, Sunil
Formato: clinical trial diagnostic images pictorial research tables/charts Journal Article
Publicado: Sage Publications Inc. Oct2016
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Oct2016
      vid: 125
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      pub: Sage Publications Inc.
      place: Thousand Oaks, California
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        10.1177/0003489416655353
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        atl: Quantitative Evaluation of Adult Subglottic Stenosis Using Intraoperative Long-range Optical Coherence Tomography.
      aug:
        au:
          Sharma, Giriraj K.
          Chin Loy, Anthony
          Su, Erica
          Jing, Joe
          Chen, Zhongping
          Wong, Brian J-F.
          Verma, Sunil
        affil: Department of Otolaryngology-Head and Neck Surgery, University of California, Irvine, California, USA
      sug:
        subj:
          Constriction, Pathologic Surgery
          Tomography, Optical Coherence
          Glottis Surgery
          Intraoperative Care
          Endoscopy Methods
          Imaging, Three-Dimensional
          Image Processing, Computer Assisted
          Glottis Anatomy and Histology
          Trachea Anatomy and Histology
          Clinical Trials
          Paired T-Tests
          P-Value
          Data Analysis Software
          Adult
          Female
          Human
          Funding Source
          Adult: 19-44 years
          Female
      ab: Objectives: To determine the feasibility of long-range optical coherence tomography (LR-OCT) as a tool to intraoperatively image and measure the subglottis and trachea during suspension microlaryngoscopy before and after endoscopic treatment of subglottic stenosis (SGS). Methods: Long-range optical coherence tomography of the adult subglottis and trachea was performed during suspension microlaryngoscopy before and after endoscopic treatment for SGS. The anteroposterior and transverse diameters, cross-sectional area (CSA), distance from the vocal cords, and length of the SGS were measured using a MATLAB software. Pre-intervention and postintervention airway dimensions were compared. Three-dimensional volumetric airway reconstructions were generated using medical image processing software (MIMICS). Results: Intraoperative LR-OCT imaging was performed in 3 patients undergoing endoscopic management of SGS. Statistically significant differences in mean anteroposterior diameter (P < .01), transverse diameter (P < .001), and CSA (P < .001) were noted between pre-intervention and postintervention data. Three-dimensional airway models were viewed in cross-sectional format and via virtual “fly through” bronchoscopy. Conclusions: This is the first report of intraoperative LR-OCT of the subglottic and tracheal airway before and after surgical management of SGS in humans. Long-range optical coherence tomography offers a practical means to measure the dimensions of SGS and acquire objective data on the response to endoscopic treatment of SGS.
      pubtype: Academic Journal
      doctype:
        clinical trial
        diagnostic images
        pictorial
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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