Importance of re-calibration time on pulse contour analysis agreement with thermodilution measurements of cardiac output: a retrospective analysis of intensive care unit patients.

We assessed the effect of re-calibration time on cardiac output estimation and trending performance in a retrospective analysis of an intensive care unit patient population using error grid analyses. Paired thermodilution and arterial blood pressure waveform measurements (N = 2141) from 222 patient...

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Publicado en:Journal of Clinical Monitoring & Computing Vol. 30; no. 5; pp. 577 - 587
Autores principales: Scully, Christopher, Gomatam, Shanti, Forrest, Shawn, Strauss, David, Scully, Christopher G, Strauss, David G
Formato: research tables/charts Journal Article
Publicado: Springer Nature Oct2016
Acceso en línea:Ver este registro en EBSCOhost
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        atl: Importance of re-calibration time on pulse contour analysis agreement with thermodilution measurements of cardiac output: a retrospective analysis of intensive care unit patients.
      aug:
        au:
          Scully, Christopher
          Gomatam, Shanti
          Forrest, Shawn
          Strauss, David
          Scully, Christopher G
          Strauss, David G
        affil: Office of Science and Engineering Laboratories, Division of Biomedical Physics, Center for Devices and Radiological Health , U.S. Food and Drug Administration , Silver Spring USA
      sug:
        subj:
          Monitoring, Physiologic Methods
          Critical Care Methods
          Calibration
          Cardiac Output
          Thermodilution Methods
          Middle Age
          Blood Pressure
          Algorithms
          Retrospective Design
          Resource Databases
          Reproducibility of Results
          Time Factors
          Arterial Pressure
          Female
          Male
          Intensive Care Units
          Heart Rate
          Aged
          Human
          Middle Aged: 45-64 years
          Aged: 65+ years
          Female
          Male
      ab: We assessed the effect of re-calibration time on cardiac output estimation and trending performance in a retrospective analysis of an intensive care unit patient population using error grid analyses. Paired thermodilution and arterial blood pressure waveform measurements (N = 2141) from 222 patient records were extracted from the Multiparameter Intelligent Monitoring in Intensive Care II database. Pulse contour analysis was performed by implementing a previously reported algorithm at calibration times of 1, 2, 8 and 24 h. Cardiac output estimation agreement was assessed using Bland-Altman and error grid analyses. Trending was assessed by concordance and a 4-Quadrant error grid analysis. Error between pulse contour and thermodilution increased with longer calibration times. Limits of agreement were -1.85 to 1.66 L/min for 1 h maximum calibration time compared to -2.70 to 2.41 L/min for 24 h. Error grid analysis resulted in 74.2 % of points bounded by 20 % error limits of thermodilution measurements for 1 h calibration time compared to 65 % for 24 h. 4-Quadrant error grid analysis showed <75 % of changes in pulse contour estimates to be within ±80 % of the change in the thermodilution measurement at any calibration time. Shorter calibration times improved the agreement of cardiac output pulse contour estimates with thermodilution. Use of minimally invasive pulse contour methods in intensive care monitoring could benefit from prospective studies evaluating calibration protocols. The applied pulse contour analysis method and thermodilution showed poor agreement to monitor changes in cardiac output.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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