Rapid breath-hold assessment of myocardial velocities using spiral UNFOLD-ed SENSE tissue phase mapping.
Purpose: To develop and validate a rapid breath-hold tissue phase mapping (TPM) sequence.Materials and Methods: The sequence was based on an efficient uniform density spiral acquisition, combined with data acceleration. A novel acquisition and reconstruction strategy enabled combination of UNFOLD (2...
| Publicado en: | Journal of Magnetic Resonance Imaging Vol. 44; no. 4; pp. 1003 - 1010 |
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| Autores principales: | , , , |
| Formato: | research Journal Article |
| Publicado: |
Wiley-Blackwell
Oct2016
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=118172659&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 118172659 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 10531807 O63 jtl: Journal of Magnetic Resonance Imaging issn: 10531807 maglogo: Y pubinfo: dt: Oct2016 vid: 44 iid: 4 pid: 480 pub: Wiley-Blackwell place: Malden, Massachusetts artinfo: ui: 118172659 118172659 NLM26929195 118172659 10.1002/jmri.25218 NLM26929195 118172659 ppf: 1003 ppct: 7 formats: tig: atl: Rapid breath-hold assessment of myocardial velocities using spiral UNFOLD-ed SENSE tissue phase mapping. aug: au: Kowalik, Grzegorz T. Muthurangu, Vivek Khushnood, Abbas Steeden, Jennifer A. affil: UCL Centre for Cardiovascular Imaging, University College London, London UK sug: subj: Aortic Valve Physiopathology Heart Valve Diseases Magnetic Resonance Imaging Methods Heart Valve Diseases Physiopathology Aortic Valve Breath Holding Signal Processing, Computer Assisted Adult Male Middle Age Aged Sensitivity and Specificity Cardiac-Gated Imaging Techniques Methods Image Interpretation, Computer Assisted Methods Reproducibility of Results Human Validation Studies Comparative Studies Evaluation Research Multicenter Studies Funding Source Adult: 19-44 years Middle Aged: 45-64 years Aged: 65+ years Male ab: Purpose: To develop and validate a rapid breath-hold tissue phase mapping (TPM) sequence.Materials and Methods: The sequence was based on an efficient uniform density spiral acquisition, combined with data acceleration. A novel acquisition and reconstruction strategy enabled combination of UNFOLD (2×) and SENSE (3×): UNFOLD-ed SENSE. The sequence was retrospectively cardiac-gated, and a graphics processing unit (GPU) was used for rapid "online" reconstruction. The optimal UNFOLD parameters for the data were calculated using an in silico model. The technique was validated on a 1.5T MR scanner in 15 patients with known aortic valve disease, against a respiratory self-navigated free-breathing TPM technique. Quantitative image quality measures (velocity-to-noise and edge sharpness) were made as well as calculation of longitudinal, radial, and tangential myocardial velocities in the left ventricle.Results: The proposed breath-hold TPM data took eight heartbeats to acquire. The breath-hold TPM images had significantly higher edge sharpness (P = 0.0014) than the self-navigated TPM images, but with significantly lower velocity-to-noise ratio (P < 0.0001). There was excellent agreement (r > 0.94) in the longitudinal, radial, and tangential velocities between the self-navigated data and the proposed breath-hold TPM sequence.Conclusion: We demonstrate the feasibility of using spiral UNFOLD-ed SENSE to measure myocardial velocities using a rapid breath-hold spiral TPM sequence. This novel technique might enable accurate measurement of myocardial velocities, in a short scan time, which is especially important in a busy clinical workflow. J. MAGN. RESON. IMAGING 2016;44:1003-1009. pubtype: Academic Journal doctype: research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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