Smoothed l0 Norm Regularization for Sparse-View X-Ray CT Reconstruction.

Low-dose computed tomography (CT) reconstruction is a challenging problem in medical imaging. To complement the standard filtered back-projection (FBP) reconstruction, sparse regularization reconstruction gains more and more research attention, as it promises to reduce radiation dose, suppress artif...

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Published in:BioMed Research International Vol. 2016; pp. 1 - 13
Main Authors: Li, Ming, Zhang, Cheng, Peng, Chengtao, Guan, Yihui, Xu, Pin, Sun, Mingshan, Zheng, Jian
Format: equations & formulas research tables/charts Journal Article
Published: Wiley-Blackwell 9/20/2016
Online Access:View this record in EBSCOhost
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      dt: 9/20/2016
      vid: 2016
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      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        10.1155/2016/2180457
        118218662
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        atl: Smoothed l0 Norm Regularization for Sparse-View X-Ray CT Reconstruction.
      aug:
        au:
          Li, Ming
          Zhang, Cheng
          Peng, Chengtao
          Guan, Yihui
          Xu, Pin
          Sun, Mingshan
          Zheng, Jian
        affil: Medical Imaging Department, Suzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences, Suzhou 215163, China
      sug:
        subj:
          Diagnostic Imaging Methods
          Tomography, X-Ray Computed Evaluation
          Radiography
          Radiation Adverse Effects
          Radiation Dosage
          Funding Source
      ab: Low-dose computed tomography (CT) reconstruction is a challenging problem in medical imaging. To complement the standard filtered back-projection (FBP) reconstruction, sparse regularization reconstruction gains more and more research attention, as it promises to reduce radiation dose, suppress artifacts, and improve noise properties. In this work, we present an iterative reconstruction approach using improved smoothed l0 (SL0) norm regularization which is used to approximate l0 norm by a family of continuous functions to fully exploit the sparseness of the image gradient. Due to the excellent sparse representation of the reconstruction signal, the desired tissue details are preserved in the resulting images. To evaluate the performance of the proposed SL0 regularization method, we reconstruct the simulated dataset acquired from the Shepp-Logan phantom and clinical head slice image. Additional experimental verification is also performed with two real datasets from scanned animal experiment. Compared to the referenced FBP reconstruction and the total variation (TV) regularization reconstruction, the results clearly reveal that the presented method has characteristic strengths. In particular, it improves reconstruction quality via reducing noise while preserving anatomical features.
      pubtype: Academic Journal
      doctype:
        equations & formulas
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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