Using Innovative Acoustic Analysis to Predict the Postoperative Outcomes of Unilateral Vocal Fold Paralysis.

Objective. Autologous fat injection laryngoplasty is ineffective for some patients with iatrogenic vocal fold paralysis, and additional laryngeal framework surgery is often required. An acoustically measurable outcome predictor for lipoinjection laryngoplasty would assist phonosurgeons in formulatin...

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Published in:BioMed Research International Vol. 2016; pp. 1 - 10
Main Authors: Tsou, Yung-An, Liu, Yi-Wen, Chang, Wen-Dien, Chen, Wei-Chen, Ke, Hsiang-Chun, Lin, Wen-Yang, Yang, Hsing-Rong, Shie, Dung-Yun, Tsai, Ming-Hsui
Format: equations & formulas pictorial research tables/charts tracings Journal Article
Published: Wiley-Blackwell 9/21/2016
Online Access:View this record in EBSCOhost
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        23146133
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      jtl: BioMed Research International
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      dt: 9/21/2016
      vid: 2016
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      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        118242624
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        10.1155/2016/7821415
        118242624
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        atl: Using Innovative Acoustic Analysis to Predict the Postoperative Outcomes of Unilateral Vocal Fold Paralysis.
      aug:
        au:
          Tsou, Yung-An
          Liu, Yi-Wen
          Chang, Wen-Dien
          Chen, Wei-Chen
          Ke, Hsiang-Chun
          Lin, Wen-Yang
          Yang, Hsing-Rong
          Shie, Dung-Yun
          Tsai, Ming-Hsui
        affil: Department of Otolaryngology, China Medical University Hospital, Taichung, Taiwan
      sug:
        subj:
          Vocal Cord Paralysis Surgery
          Postoperative Care
          Diffusion of Innovation
          Human
          Acoustics
          Thyroid Diseases Surgery
          Treatment Failure
          Vocal Cord Paralysis Symptoms
          Voice Disorders
          Funding Source
      ab: Objective. Autologous fat injection laryngoplasty is ineffective for some patients with iatrogenic vocal fold paralysis, and additional laryngeal framework surgery is often required. An acoustically measurable outcome predictor for lipoinjection laryngoplasty would assist phonosurgeons in formulating treatment strategies. Methods. Seventeen thyroid surgery patients with unilateral vocal fold paralysis participated in this study. All subjects underwent lipoinjection laryngoplasty to treat postsurgery vocal hoarseness. After treatment, patients were assigned to success and failure groups on the basis of voice improvement. Linear prediction analysis was used to construct a new voice quality indicator, the number of irregular peaks (NIrrP). It compared with the measures used in the Multi-Dimensional Voice Program (MDVP), such as jitter (frequency perturbation) and shimmer (perturbation of amplitude). Results. By comparing the [i] vowel produced by patients before the lipoinjection laryngoplasty (AUC = 0.98, 95% CI = 0.78–0.99), NIrrP was shown to be a more accurate predictor of long-term surgical outcomes than jitter (AUC = 0.73, 95% CI = 0.47–0.91) and shimmer (AUC = 0.63, 95% CI = 0.37–0.85), as identified by the receiver operating characteristic curve. Conclusions. NIrrP measured using the LP model could be a more accurate outcome predictor than the parameters used in the MDVP.
      pubtype: Academic Journal
      doctype:
        equations & formulas
        pictorial
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        tracings
        Journal Article
      ougenre: Article
    language: English
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