Challenging a dogma: co-mutations exist in MAPK pathway genes in colorectal cancer.
Sequencing of genes encoding mitogen-activated protein kinase (MAPK) pathway proteins in colorectal cancer (CRC) has established as dogma that of the genes in a pathway only a single one is ever mutated. We searched for cases with a mutation in more than one MAPK pathway gene (co-mutations). Tumor t...
| Publicado en: | Virchows Archiv: European Journal of Pathology Vol. 469; no. 4; pp. 459 - 465 |
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| Autores principales: | , , , , , , |
| Formato: | Journal Article |
| Publicado: |
Springer Nature
Oct2016
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| Acceso en línea: | Ver este registro en EBSCOhost |