Structural and sequence analysis of class A β-lactamases with respect to avibactam inhibition: impact of Ω-loop variations.
Background: There exists a significant diversity among class A β-lactamases and the proliferation of these enzymes is a significant medical concern due to the ability of some members to efficiently hydrolyse both extended-spectrum cephalosporins and carbapenems. Avibactam is a novel non-β-lactam β-l...
| Published in: | Journal of Antimicrobial Chemotherapy (JAC) Vol. 71; no. 10; pp. 2848 - 2856 |
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| Main Authors: | , , , |
| Format: | research tables/charts Journal Article |
| Published: |
Oxford University Press / USA
Oct2016
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| Online Access: | View this record in EBSCOhost |