Does youth adiposity, or change in adiposity from youth to adulthood, predict metabolically healthy obesity in adulthood?

Summary: Background: Individuals with metabolically healthy obesity (MHO) do not have the metabolic complications usually associated with obesity. Objective: To examine whether youth adiposity, or change in adiposity from youth to adulthood, predicts MHO 20 years later. Methods: A national sample of...

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Publicado en:Pediatric Obesity Vol. 11; no. 5; pp. 349 - 354
Autores principales: Smith, K. J., Bessell, E., Magnussen, C. G., Dwyer, T., Venn, A. J.
Formato: research tables/charts Journal Article
Publicado: Wiley-Blackwell Oct2016
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Oct2016
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      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        atl: Does youth adiposity, or change in adiposity from youth to adulthood, predict metabolically healthy obesity in adulthood?
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        au:
          Smith, K. J.
          Bessell, E.
          Magnussen, C. G.
          Dwyer, T.
          Venn, A. J.
        affil: Menzies Institute for Medical Research, University of Tasmania, Hobart Tasmania, Australia
      sug:
        subj:
          Adipose Tissue Distribution In Adolescence
          Obesity Risk Factors
          Human
          Child
          Adolescence
          Young Adult
          Adult
          Australia
          Body Mass Index
          Body Weight Changes
          Female
          Male
          Descriptive Statistics
          Relative Risk
          Regression
          Confidence Intervals
          Child: 6-12 years
          Adolescent: 13-18 years
          Adult: 19-44 years
          Female
          Male
      ab: Summary: Background: Individuals with metabolically healthy obesity (MHO) do not have the metabolic complications usually associated with obesity. Objective: To examine whether youth adiposity, or change in adiposity from youth to adulthood, predicts MHO 20 years later. Methods: A national sample of 2410 Australian participants had height, weight and waist circumference (WC) measured in 1985 (7–15 years old) and 2004–2006 (26–36 years old). A fasting blood sample was taken in 2004–2006. MHO was defined as body mass index (BMI) ≥30 kg m−2, normal fasting glucose (<5.6 mmol L−1), triglycerides (<1.695 mmol L−1), high‐density lipoprotein‐cholesterol (>1.036 mmol L−1 men, > 1.295 mmol L−1 women), blood pressure (<130/85 mmHg) and no medication for these conditions. Relative risks (RR) were calculated using log binomial regression and expressed per unit of youth BMI (or WC) z‐score or change in BMI (or WC) z‐score from youth to adulthood, adjusted for sex and youth age. Results: In total 323 individuals were obese at follow‐up, 79 (24.5%) were MHO. Adult MHO was not associated with youth BMI (RR: 1.00, 95%CI: 0.85–1.19) or WC (RR: 0.93, 95%CI: 0.79–1.11). Individuals were less likely to be MHO if they had larger increases in BMI (BMI RR: 0.74, 95%CI: 0.57–0.97) or WC (RR: 0.70, 95%CI: 0.55–0.90) from youth to adulthood. Conclusions: Change in adiposity from youth to adulthood predicted adult MHO better than youth adiposity alone.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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