| Sumario: | Aim: identify the most frequent nursing diagnoses in patients with multiple sclerosis hospitalized in a neurological unit. Method: This is a cross-sectional, quantitative study, conducted in the period from January to August 2014 with 58 patients in a teaching hospital in northeastern Brazil, following the relevant steps: data collection through validated instrument; process analysis and validation in pairs according to the nursing diagnoses; and, finally, inferential analysis. Results: 30 nursing diagnoses were identified, the most common were: impaired physical mobility; activity intolerance, impaired urinary excretion; impaired memory; impaired pattern of sleep; self-ca re deficit for feeding; ineffective coping; constipation; sexual dysfunction and chronic pain. Conclusion: The most common diagnoses identified are in the fields of activity/rest, disposal and exchange coping/stress tolerance, perception/cognition, comfort and sexuality.
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